一甲胺作为非甲基营养型细菌根瘤农杆菌的氮源。
Monomethylamine as a nitrogen source for a nonmethylotrophic bacterium, Agrobacterium tumefaciens.
机构信息
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
出版信息
Appl Environ Microbiol. 2010 Jun;76(12):4102-4. doi: 10.1128/AEM.00469-10. Epub 2010 Apr 16.
Abstract
Monomethylamine can be used by nonmethylotrophs as a sole nitrogen source but not as a carbon source; however, little is known about the genes and enzymes involved. The gamma-glutamylmethylamide/N-methylglutamate pathway for monomethylamine utilization by methylotrophs has recently been resolved. We have identified genes encoding key enzymes of this pathway in nonmethylotrophs (e.g., Agrobacterium tumefaciens) and demonstrated that this pathway is also involved in the utilization of monomethylamine as a nitrogen source by nonmethylotrophs.
摘要
一甲胺可以被非甲基营养菌用作唯一的氮源，但不能用作碳源；然而，人们对涉及的基因和酶知之甚少。最近已经解决了甲基营养菌利用γ-谷氨酰甲基酰胺/N-甲基谷氨酸途径利用一甲胺的问题。我们已经在非甲基营养菌（如根瘤农杆菌）中鉴定出编码该途径关键酶的基因，并证明该途径也参与非甲基营养菌将一甲胺作为氮源的利用。
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