Department of Food and Nutrition, Japan Women's University, 2-8-1, Mejirodai, Bunkyo-ku, Tokyo, 112-8681 Tokyo, Japan.
Prev Med. 2010 Jul;51(1):11-7. doi: 10.1016/j.ypmed.2010.04.008. Epub 2010 Apr 18.
An effective program for preventing metabolic diseases through lifestyle modification is urgently needed. We investigated the effects of the Life Style Modification Program for Physical Activity and Nutrition program (LiSM10!) on metabolic parameters in middle-aged male Japanese white-collar workers.
One hundred and one male office workers, 30 to 59 years of age, with metabolic syndrome risk factors, were randomly allocated into no-treatment control (n=49) and LiSM intervention (n=52) groups. The LiSM group attended individualized assessment and collaborative goal setting sessions based on food group intake and physical activity, followed by two individual counseling sessions with a registered dietitian and physical trainer, and received monthly website advice during the 4-month period from December 2006 to May 2007, in Tokyo, Japan. They were encouraged to enter current targeted food intakes and pedometer data on self-monitoring websites during the entire study period.
Habitual food group intakes changed significantly in the LiSM group, showing improvements in 14 anthropometric and biochemical parameters contributing to inter-group differences in body weight, body mass index, fasting plasma glucose, insulin and homeostasis model assessment of insulin resistance changes (p<0.01).
The LiSM10! program effectively improved insulin resistance-related metabolic parameters in middle-aged male white-collar workers.
迫切需要通过生活方式改变来预防代谢性疾病的有效计划。我们研究了生活方式改变计划对体育活动和营养计划（LiSM10！）对中年日本男性白领代谢参数的影响。
将 101 名 30 至 59 岁有代谢综合征危险因素的男性办公室工作人员随机分配到无治疗对照组（n=49）和 LiSM 干预组（n=52）。LiSM 组根据食物组摄入量和身体活动接受个体化评估和协作目标设定会议，然后由注册营养师和体能教练进行两次个体咨询，并在 2006 年 12 月至 2007 年 5 月的 4 个月期间每月在网站上提供建议，地点在日本东京。他们被鼓励在整个研究期间在自我监测网站上输入当前的目标食物摄入量和计步器数据。
LiSM 组的习惯性食物组摄入量发生了显著变化，体重、体重指数、空腹血糖、胰岛素和稳态模型评估的胰岛素抵抗变化的 14 个体型和生化参数改善（p<0.01）。
LiSM10！计划有效改善了中年男性白领与胰岛素抵抗相关的代谢参数。
