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急性阑尾炎——开放手术还是微创手术?

Acute appendicitis--open or minimally-invasive approach?

作者信息

Moldovanu R, Vlad N, Târcoveanu E, Dimofte G, Lupaşcu C, Filip V, Bradea C, Răileanu G, Tuţuianu B, Crumpei F

机构信息

First Surgical Unit, "St. Spiridon" Hospital, "Gr. T. Popa" University of Medicine and Pharmacy, Iaşi, Romania.

出版信息

Chirurgia (Bucur). 2010 Jan-Feb;105(1):45-51.

Abstract

BACKGROUND

Although laparoscopy has become the standard approach in other procedures, this technique is not generally accepted for acute appendicitis.

AIM

To evaluate the results after minimally invasive appendectomies.

METHODS

All medical records of patients operated for acute appendicitis during the last year were retrospectively reviewed. We considered only patients with diagnosis of acute appendicitis confirmed by histopathology. We designed two groups: operated by open approach (OA) and operated by minimally-invasive approach (MIA). The two groups were compared for differenced in homogeneity and main end results: morbidity, mortality, hospital stay.

RESULTS

The men/women ratio was 112/88 (1.27), with a mean age of 31.83 +/- 1.06 years. There were more women in the MIA and more men in the OA group, p = 0.001. The Alvarado score was significant lower in MIA group (5.69 +/- 0.24 versus 6.57 +/- 0.23, p = 0.009). Comorbidities were noted in 51% from the patients, most of them in MIA group: 58.8%; N = 60, p = 0.016. Mean operation time was similar in both groups: 36.96 +/- 1.48 in OA versus 37.03 +/- 1.39 minutes in MIA. The postoperative mortality rate was 0.5%. The postoperative morbidity rate was 12%. Even though the number of cases with postoperative complications were double in OA group (16 cases versus 8 cases in MIA group) it did not reach statistical significance, p = 0.073. Histopathological examinations revealed early acute appendicitis in 45.5% cases (N = 91), suppurative appendicitis in 46.5% (N = 93) and gangrenous appendicitis in 8% (N = 16); early acute appendicitis was more frequent in MIA group and suppurative appendicitis in OA group: p = 0.017. The hospital stay was similar in both groups: 4.34 +/- 0.39 in OA versus 3.58 +/- 0.25 days in MIA group; p = 0.103.

CONCLUSIONS

MIA is a safe procedure and can be performed even in the patients with comorbidities. We didn't find any statistical significant difference from point of view of postoperative morbidity; however more postoperative complications were find in OA vs MIA group. The postoperative hospital stay was similar in both groups.

摘要

背景

尽管腹腔镜检查已成为其他手术的标准方法,但该技术在急性阑尾炎手术中尚未被广泛接受。

目的

评估微创阑尾切除术后的效果。

方法

回顾性分析去年因急性阑尾炎接受手术治疗的所有患者的病历。仅纳入经组织病理学确诊为急性阑尾炎的患者。我们将患者分为两组:开放手术组(OA)和微创手术组(MIA)。比较两组在同质性和主要结局方面的差异:发病率、死亡率、住院时间。

结果

男女比例为112/88(1.27),平均年龄为31.83±1.06岁。MIA组女性较多,OA组男性较多,p = 0.001。MIA组的阿尔瓦拉多评分显著低于OA组(5.69±0.24对6.57±0.23,p = 0.009)。51%的患者有合并症,其中大多数在MIA组:58.8%;N = 60,p = 0.016。两组的平均手术时间相似:OA组为36.96±1.48分钟,MIA组为37.03±1.39分钟。术后死亡率为0.5%。术后发病率为12%。尽管OA组术后并发症的病例数是MIA组的两倍(16例对8例),但未达到统计学显著性,p = 0.073。组织病理学检查显示,45.5%的病例(N = 91)为早期急性阑尾炎,46.5%(N = 93)为化脓性阑尾炎,8%(N = 16)为坏疽性阑尾炎;MIA组早期急性阑尾炎更为常见,OA组化脓性阑尾炎更为常见:p = 0.017。两组的住院时间相似:OA组为4.34±0.39天,MIA组为3.58±0.25天;p = 0.103。

结论

MIA是一种安全的手术方法,即使在有合并症的患者中也可进行。从术后发病率的角度来看,我们未发现任何统计学上的显著差异;然而,OA组的术后并发症比MIA组更多。两组的术后住院时间相似。

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