Epidemiology Postgraduate Program, Federal University of Pelotas, Pelotas, Brazil.
Obes Rev. 2011 Feb;12(2):93-104. doi: 10.1111/j.1467-789X.2010.00741.x.
Asthma and obesity, both of which are considered global health issues, affect approximately 300 million individuals worldwide. The observation that asthma and obesity tend to increase in parallel may indicate a potential link between these two conditions. The aim of this systematic review of the literature was to investigate the relationship between childhood nutritional status and incidence or persistence of asthma during adolescence. The principal eligibility criteria for selection of articles were including longitudinal analysis, and which measured of exposure during childhood or adolescence and outcome during adolescence. The systematic search initially returned 1563 unique articles. After inspection of titles and reading the abstracts of these articles, we chose 27 for full reading. Of these, 10 were selected to be included in the present review. Of the 10 selected studies, eight showed positive associations between overweight/obesity and asthma. Of these, two were independent of sex, three were found only among men and another three only among women. The present study shows strong evidence that, although the role of sex is not clear, obesity precedes, and is associated with, the persistence and intensity of symptoms of asthma.
哮喘和肥胖均被视为全球性健康问题，影响着全球约 3 亿人口。观察到哮喘和肥胖的发病率呈平行上升趋势，这可能表明这两种疾病之间存在潜在联系。本系统文献回顾的目的是研究儿童营养状况与青少年期哮喘发病或持续存在之间的关系。选择文章的主要入选标准为包括纵向分析，并在儿童期或青春期测量暴露情况，以及在青春期测量结果。系统搜索最初返回了 1563 篇独特的文章。在检查了这些文章的标题并阅读了摘要之后，我们选择了 27 篇进行全文阅读。其中，有 10 篇被选入本次综述。在所选择的 10 项研究中，有 8 项表明超重/肥胖与哮喘之间存在正相关关系。其中，有 2 项与性别无关，有 3 项仅在男性中发现，另外 3 项仅在女性中发现。本研究有力地表明，尽管性别作用尚不清楚，但肥胖是哮喘症状持续存在和加重的前兆，并与之相关。
