Institute of Legal Medicine, Johannes Gutenberg-University Mainz, Am Pulverturm 3, Mainz, Germany.
J Anal Toxicol. 2010 Apr;34(3):155-61. doi: 10.1093/jat/34.3.155.
The Rapid Stat assay, a point-of-collection drug-testing device for detection of amphetamines, cannabinoids, cocaine, opiates, methadone, and benzodiazepines in oral fluid, was evaluated for cannabis and amphetamine-type stimulants. The Rapid Stat tests (n = 134) were applied by police officers in routine traffic checks. Oral fluid and blood samples were analyzed using gas chromatography-mass spectrometry (GC-MS) for Delta(9)-tetrahydrocannabinol, amphetamine, methamphetamine, methylenedioxymethamphetamine, methylenedioxyethylamphetamine, and methylenedioxyamphetamine. The comparison of GC-MS analysis of oral fluid with the Rapid Stat results for cannabis showed a sensitivity of 85%, a specificity of 87%, and a total confirmation rate of 87%. When compared with serum, the sensitivity of the cannabis assay decreased to 71%, the specificity to 60%, and the total confirmation rate to 66%. These findings were possibly caused by an incorrect reading of the THC test results. Comparison of the Rapid Stat amphetamine assay with GC-MS in oral fluid showed a sensitivity of 94%, a specificity of 97%, and a total confirmation rate of 97%. Compared with serum, a sensitivity of 100%, a specificity of 90%, and a total confirmation rate of 92% was found. The amphetamine assay must, therefore, be regarded as satisfactory.
快速点检测试（Rapid Stat）是一种用于检测唾液中安非他命类兴奋剂、大麻、可卡因、阿片类、美沙酮和苯二氮䓬类药物的即时检测设备，本研究对其进行了大麻和苯丙胺类兴奋剂的评估。快速点检测试（Rapid Stat）（n = 134）由警察在日常交通检查中使用。唾液和血液样本使用气相色谱-质谱法（GC-MS）分析，以检测 δ-9-四氢大麻酚、苯丙胺、甲基苯丙胺、亚甲二氧基甲基苯丙胺、亚甲二氧基乙基苯丙胺和亚甲二氧基苯丙胺。GC-MS 分析与快速点检测试大麻结果的比较显示，大麻检测的敏感性为 85%，特异性为 87%，总确认率为 87%。与血清相比，大麻检测的敏感性下降至 71%，特异性下降至 60%，总确认率下降至 66%。这可能是由于 THC 测试结果的误读所致。快速点检测试（Rapid Stat）安非他命检测与唾液中的 GC-MS 比较，敏感性为 94%，特异性为 97%，总确认率为 97%。与血清相比，敏感性为 100%，特异性为 90%，总确认率为 92%。因此，安非他命检测必须被认为是令人满意的。
