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勿食西红柿:胃食管反流病患者自述症状病因。

Don't eat tomatoes: patient's self-reported experiences of causes of symptoms in gastro-oesophageal reflux disease.

机构信息

Faculty of Society and Health, Bucks New University, Uxbridge, Buckinghamshire, UK.

出版信息

Fam Pract. 2010 Aug;27(4):410-7. doi: 10.1093/fampra/cmq020. Epub 2010 Apr 20.

Abstract

BACKGROUND

About 30-50% of patients with gastro-oesophageal reflux disease (GORD) experience refractory symptoms despite taking proton pump inhibitors regularly. Epidemiology studies suggest lifestyle risks, but these are under-represented in existing guidelines. The potential for changes to positively impact on symptoms may be underestimated. Lifestyle advice currently appears to be ineffective.

OBJECTIVES

To inform the future design of a behaviour change intervention aimed at improving symptoms for patients with GORD, by exploring patient understanding and experiences of lifestyle influences on GORD symptoms.

METHODS

We conducted semi-structured interviews with 23 patients (12 women and 11 men) aged 30-86 years, aiming to identify lifestyle influences perceived by patients to affect their symptoms.

RESULTS

Patients reported a wide range of daily influences on their symptoms, including diet, drinking with a meal, body position, alcohol, gaining weight, stress and anxiety. Dietary influences included types of food eaten and eating pattern-including speed of eating and meal size. Many foods were identified as troublesome, but not all foods affected all patients. Eating late and daytime tiredness were not recognized as causes or consequences of night-time reflux.

CONCLUSIONS

Patients stated that daily living patterns affected their reflux symptoms, but influences were highly variable between respondents. Lifestyle factors appear to combine in unique patterns for individuals, but GORD patients may not be able to identify potential triggers and make changes for themselves. A behaviour change intervention might prove beneficial to these patients.

摘要

背景

尽管质子泵抑制剂(PPI)的使用较为普遍,但仍有 30%-50%的胃食管反流病(GORD)患者出现难治性症状。流行病学研究提示生活方式风险,但这些因素在现有的指南中并没有得到充分体现。因此,可能存在一些能够改善症状的生活方式改变,但这些改变被低估了。目前,生活方式建议似乎没有效果。

目的

通过探索生活方式对 GORD 症状的影响,了解患者对其的理解和体验,为未来旨在改善 GORD 患者症状的行为改变干预措施的设计提供信息。

方法

我们对 23 名年龄在 30-86 岁的患者(12 名女性和 11 名男性)进行了半结构化访谈,旨在确定患者认为会影响其症状的生活方式影响因素。

结果

患者报告了日常生活中对其症状有广泛影响的因素,包括饮食、与进餐同时饮酒、体位、酒精、体重增加、压力和焦虑。饮食影响因素包括所吃食物的类型和进食模式,包括进食速度和餐量。许多食物被认为是麻烦的,但并非所有食物都会影响所有患者。患者并没有意识到进食过晚和白天疲劳是夜间反流的原因或后果。

结论

患者表示日常生活模式会影响他们的反流症状,但影响因素在不同患者之间存在很大差异。生活方式因素似乎在个体中以独特的模式组合出现,但 GORD 患者可能无法识别潜在的触发因素并自行做出改变。行为改变干预措施可能对这些患者有益。

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