Department of Pathology, Magee-Women's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Int J Gynecol Pathol. 2010 May;29(3):243-7. doi: 10.1097/PGP.0b013e3181c18523.
A 42-year-old woman presented with localized irritation, erythema and sharp pain in the one breast. After unsuccessful treatment for mastitis, an oncology consultation was obtained. A breast biopsy revealed an invasive carcinoma and a diagnosis of inflammatory breast cancer was made. The patient was treated with neo-adjuvant chemotherapy and subsequently underwent bilateral mastectomy. A total abdominal hysterectomy and bilateral salpingo-oophorectomy was also performed at the same time due to the presence of a pelvic mass. Morphologic and immunohistochemical examination of the specimens helped to clarify the correct diagnosis of primary ovarian carcinoma with widespread metastases to bilateral breasts.
一位 42 岁女性因单侧乳房局部刺激、红斑和剧烈疼痛就诊。在乳腺炎治疗失败后,进行了肿瘤学咨询。乳房活检显示为浸润性癌,诊断为炎性乳腺癌。患者接受了新辅助化疗,随后进行了双侧乳房切除术。由于存在盆腔肿块,同时进行了全子宫切除术和双侧输卵管卵巢切除术。标本的形态学和免疫组织化学检查有助于明确双侧乳房广泛转移的原发性卵巢癌的正确诊断。