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瑞典某医院地板抛光剂去除和应用过程中清洁工的临床体征和症状的现场研究。

A field study on clinical signs and symptoms in cleaners at floor polish removal and application in a Swedish hospital.

机构信息

Uppsala University, Uppsala, Sweden.

出版信息

Int Arch Occup Environ Health. 2010 Jun;83(5):585-91. doi: 10.1007/s00420-010-0531-5. Epub 2010 Apr 21.

Abstract

AIM

To study health effects in hospital cleaners (N = 21) at floor polish removal and application.

METHODS

The cleaners were investigated before exposure (Monday = day 1), after polish removal work (day 2), and after application of floor polish (day 3). Ratings of symptoms, tear-film break-up-time (BUT), nasal patency and biomarkers in nasal lavage were studied.

RESULTS

There was a significant increase both day 2 and day 3, as compared to pre-exposure, in ocular, nasal, throat symptoms, solvent smell, dyspnoea, and general symptoms such as headache and fatigue. Posterior nasal patency was decreased day 2 (p < 0.01) and day 3 (p < 0.01). No change of nasal biomarkers (ECP, MPO, lysozyme, albumin) was seen. BUT was decreased after polish removal (p < 0.01), but not after polish application. Separate test of the weekday effect in non-exposed showed slight improvements, or no change of symptoms or clinical signs from Monday to Wednesday. Air concentrations of ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monoethyl ether, dipropylene glycol monomethyl ether, diethylene glycol monoethyl ether and ethylene glycol phenyl ether 103, 666, 13,650, 7,000, 67, and 27 microg/m(3), respectively, at polish application. Glycol ether levels were reduced to 3% after 2 days and 0.3% after 17 days.

CONCLUSIONS

Emissions from a common water-based polish remover and floor polish system may cause ocular and airway irritation and general symptoms, and reduce tear-film stability and nasal patency. The levels of glycol ethers had a rapid decay.

摘要

目的

研究地板抛光去除和应用过程中医院清洁工(N=21)的健康影响。

方法

在暴露前(星期一=第 1 天)、抛光去除工作后(第 2 天)和地板抛光应用后(第 3 天)对清洁工进行调查。研究了症状评分、泪膜破裂时间(BUT)、鼻腔通畅性和鼻腔灌洗液中的生物标志物。

结果

与暴露前相比,第 2 天和第 3 天的眼部、鼻部、喉部症状、溶剂气味、呼吸困难以及头痛和疲劳等一般症状均显著增加。第 2 天(p<0.01)和第 3 天(p<0.01)后鼻通畅性降低。未观察到鼻腔生物标志物(ECP、MPO、溶菌酶、白蛋白)的变化。抛光去除后 BUT 降低(p<0.01),但抛光应用后无变化。非暴露的工作日效应单独测试显示,从星期一到星期三,症状或临床体征略有改善或无变化。在应用抛光剂时,乙二醇单乙醚、乙二醇单丁醚、二乙二醇单乙醚、二丙二醇单甲基醚、二乙二醇单乙基醚和乙二醇苯醚的空气浓度分别为 103、666、13、650、7、000、67 和 27μg/m(3)。第 2 天和第 17 天后,二醇醚水平分别降至 3%和 0.3%。

结论

常见的水基抛光去除剂和地板抛光系统的排放物可能会引起眼部和呼吸道刺激以及一般症状,并降低泪膜稳定性和鼻腔通畅性。二醇醚的水平迅速下降。

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