Yang Yong, Sun Dongchong, Wei Zhitao, Xu Feng, Hong Baofa, Zhang Xu
Department of Urology, People's Liberation Army General Hospital, Beijing, 100853, China.
J Huazhong Univ Sci Technolog Med Sci. 2010 Apr;30(2):198-200. doi: 10.1007/s11596-010-0213-2. Epub 2010 Apr 21.
In this study, the vaporization ratio of the 2-mum laser in the prostatic tissue with benign prostatic hyperplasia was examined in vitro, to explore a technique to estimate the clearance rate of prostatic tissue during the transurethral vaporesection of the prostate. A total of 9 fresh prostatic tissue specimens were obtained by open surgery and the wet weight of the prostatic tissue were measured immediately after the sample collection. Under the simulated conditions of transurethral vaporesection of the prostate by 2-microm laser, each prostate gland was completely vaporesected into fragments with a diameter of less than 1.0 cm in vitro. After the vaporesection, the whole fragments of prostatic tissue were collected and measured. Then the lost weight of prostatic tissue, the weight of the collected prostatic tissue and the ratio of the lost weight of prostatic tissue to the wet weight of the prostate glandular organ specimen were calculated. The correlation between the weight of collected prostatic tissue and the weight of the whole glandular organ was analyzed. All the experimental procedures were carried out by one operator. Wet weight of the prostatic gland specimen and the weight of the harvested prostatic tissues after the procedure were recorded. With respect to the wet weight of prostate gland specimen, the percentage of the weight of collected prostatic tissue was (34.45 + or - 1.51) %, and the percentage of the lost weight of prostatic tissue was (65.55 + or - 1.51)%. Satisfactory linear relationship was observed between the weight of collected prostatic tissue and the wet weight of prostate gland specimen [y = 3.245 x -6.475 (t=15.097, P=0.000)]. It is concluded that under the simulated conditions of transurethral vaporesection of the prostate by 2-mum laser, the vaporization ratio of prostatic tissue can be calculated on the basis of the weight of collected prostatic tissue, and thereby the clearance of prostatic tissue during the formal operation by 2-microm laser could be quantitatively determined.
在本研究中，体外检测了2微米激光在良性前列腺增生前列腺组织中的汽化率，以探索一种在经尿道前列腺汽化切除术期间估计前列腺组织清除率的技术。通过开放手术共获取9个新鲜前列腺组织标本，并在样本采集后立即测量前列腺组织的湿重。在2微米激光经尿道前列腺汽化切除术的模拟条件下，每个前列腺在体外被完全汽化成直径小于1.0厘米的碎片。汽化切除术后，收集并测量前列腺组织的全部碎片。然后计算前列腺组织的失重、收集的前列腺组织重量以及前列腺组织失重与前列腺器官标本湿重的比值。分析收集的前列腺组织重量与整个腺体器官重量之间的相关性。所有实验步骤均由一名操作人员完成。记录前列腺标本的湿重以及手术后收获的前列腺组织重量。就前列腺标本的湿重而言，收集的前列腺组织重量百分比为(34.45±1.51)%，前列腺组织失重百分比为(65.55±1.51)%。观察到收集的前列腺组织重量与前列腺标本湿重之间存在良好的线性关系[y = 3.245x - 6.475 (t = 15.097, P = 0.000)]。得出结论，在2微米激光经尿道前列腺汽化切除术的模拟条件下，可根据收集的前列腺组织重量计算前列腺组织的汽化率，从而可定量确定2微米激光正式手术期间前列腺组织的清除情况。
