Department of Urology, Shanghai First People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200080, China.
Asian J Androl. 2011 Jul;13(4):636-9. doi: 10.1038/aja.2011.19. Epub 2011 May 16.
The purpose of the current ex vivo study was to compare the speed of vaporesection of human prostatic tissue with benign prostatic hyperplasia (BPH) and the depth of tissue damage using 70- and 120-W 2-µm laser devices. Fresh prostatic tissue specimens were obtained from five patients by open prostatectomy, and were divided into separate groups (70 and 120 W) based on the energy of the laser output (70 and 120 W, respectively). The vaporesection speed, coagulation zone depth and the necrotic tissue layer in the prostatic tissue were evaluated. The current result showed that the speeds (mean±s.d.) of vaporesection were 5.21 ± 0.66 and 10.39 ± 1.15 g/5 min for the 70 and 120 W groups, respectively (P=0.000). There was no difference in the depth of necrosis/coagulation (0.98 ± 0.13/0.30 ± 0.09 and 0.99 ± 0.12/0.31 ± 0.08 mm) for the 70 and 120 W groups, respectively. In conclusion, both 70- and 120-W 2-µm laser devices had superficial tissue damage during the vaporesection of human prostate tissue; moreover, the 120-W laser offers a higher vaporesection speed than the 70-W laser.
本体外研究的目的是比较使用 70 和 120 W 2 µm 激光设备汽化切割伴有良性前列腺增生（BPH）的人前列腺组织的速度和组织损伤深度。通过开放性前列腺切除术从五名患者中获得新鲜前列腺组织标本，并根据激光输出的能量将其分为单独的组（70 和 120 W）。评估了汽化切割速度、凝固区深度和前列腺组织中的坏死组织层。目前的结果表明，70 和 120 W 组的汽化切割速度分别为 5.21 ± 0.66 和 10.39 ± 1.15 g/5 min（P=0.000）。70 和 120 W 组的坏死/凝固深度分别为 0.98 ± 0.13/0.30 ± 0.09 和 0.99 ± 0.12/0.31 ± 0.08 mm，无差异。总之，在人前列腺组织的汽化切割过程中，70 和 120 W 2 µm 激光设备均造成浅层组织损伤；此外，120 W 激光比 70 W 激光具有更高的汽化切割速度。
