Morris Daniel O, Boston Raymond C, O'Shea Kathleen, Rankin Shelley C
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St., Philadelphia, PA 19104, USA.
Vet Dermatol. 2010 Aug;21(4):400-7. doi: 10.1111/j.1365-3164.2010.00866.x. Epub 2010 Apr 9.
It has been shown that people and pets can harbour identical strains of meticillin-resistant (MR) staphylococci when they share an environment. Veterinary dermatology practitioners are a professional group with a high incidence of exposure to animals infected by Staphylococcus spp. The objective of this study was to assess the prevalence of carriage of MR Staphylococcus aureus (MRSA), MR S. pseudintermedius (MRSP) and MR S. schleiferi (MRSS) by veterinary dermatology practice staff and their personal pets. A swab technique and selective media were used to screen 171 veterinary dermatology practice staff and their respective pets (258 dogs and 160 cats). Samples were shipped by over-night carrier. Human subjects completed a 22-question survey of demographic and epidemiologic data relevant to staphylococcal transmission. The 171 human-source samples yielded six MRSA (3.5%), nine MRSP (5.3%) and four MRSS (2.3%) isolates, while 418 animal-source samples yielded eight MRSA (1.9%) 21 MRSP (5%), and two MRSS (0.5%) isolates. Concordant strains (genetically identical by pulsed-field gel electrophoresis) were isolated from human subjects and their respective pets in four of 171 (2.9%) households: MRSA from one person/two pets and MRSP from three people/three pets. In seven additional households (4.1%), concordant strains were isolated from only the pets: MRSA in two households and MRSP in five households. There were no demographic or epidemiologic factors statistically associated with either human or animal carriage of MR staphylococci, or with concordant carriage by person-pet or pet-pet pairs. Lack of statistical associations may reflect an underpowered study.
研究表明，当人与宠物共处同一环境时，他们可能携带相同菌株的耐甲氧西林葡萄球菌。兽医皮肤科从业者是一个专业群体，他们接触感染葡萄球菌属动物的几率很高。本研究的目的是评估兽医皮肤科工作人员及其宠物携带耐甲氧西林金黄色葡萄球菌（MRSA）、耐甲氧西林中间型葡萄球菌（MRSP）和耐甲氧西林施氏葡萄球菌（MRSS）的情况。采用拭子技术和选择性培养基对171名兽医皮肤科工作人员及其各自的宠物（258只狗和160只猫）进行筛查。样本通过隔夜快递运送。人类受试者完成了一项包含22个问题的关于与葡萄球菌传播相关的人口统计学和流行病学数据的调查。171份人类样本中分离出6株MRSA（3.5%）、9株MRSP（5.3%）和4株MRSS（2.3%），而418份动物样本中分离出8株MRSA（1.9%）、21株MRSP（5%）和2株MRSS（0.5%）。在171户家庭中的4户（2.9%）中，从人类受试者及其各自的宠物中分离出了一致性菌株（通过脉冲场凝胶电泳基因相同）：1人/2只宠物携带MRSA，3人/3只宠物携带MRSP。在另外7户家庭（4.1%）中，仅从宠物中分离出了一致性菌株：2户家庭携带MRSA，5户家庭携带MRSP。耐甲氧西林葡萄球菌在人类或动物中的携带情况，以及人 - 宠物或宠物 - 宠物对的一致性携带情况，均无统计学上相关的人口统计学或流行病学因素。缺乏统计学关联可能反映出该研究的效力不足。
