Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO, USA.
J Vet Intern Med. 2010 Jan-Feb;24(1):132-9. doi: 10.1111/j.1939-1676.2009.0424.x.
A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization is reported in healthcare workers compared with nonhealthcare workers.
The prevalence of MRSA colonization differed in people and pets in households with healthcare workers as compared with households without healthcare workers.
A person and 1 dog or cat from 586 households defined as either a nonhealthcare (n = 213), veterinary healthcare (n = 211), or human healthcare (n = 162) worker household.
Prospective cross-sectional study. Samples from humans and pets were cultured in vitro. Staphylococcus aureus was identified as methicillin sensitive (MSSA) or MRSA with mecA polymerase chain reaction. Pulsed-field gel electrophoresis and spa-typing were used to characterize relatedness of S. aureus and MRSA and assign USA types.
The prevalence of MSSA and MRSA in humans was 21.5% (126/586) and 5.63% (33/586), respectively, and 7.85% (46/586) and 3.41% (20/586), respectively, in pets. There were no differences in prevalences of either MSSA or MRSA between household types. The proportion of MRSA among all S. aureus isolates in humans and pets was 20.8% (33/159) and 30.3% (20/66), respectively. In < 1.0% (4/586) of households, the same strain of MRSA was found in both a person and a pet.
There were no differences in the prevalences of MSSA or MRSA between healthcare worker and nonhealthcare worker households. Pets and people colonized with S. aureus were as likely to be colonized with MRSA. Colonization of a person and their pet with the same strain of MRSA was rare.
与非医护人员相比，医护人员耐甲氧西林金黄色葡萄球菌（MRSA）定植的患病率更高。
与没有医护人员的家庭相比，医护人员家庭中的人与宠物的 MRSA 定植率存在差异。
来自 586 个家庭的 1 人加 1 只狗或猫，这些家庭被定义为非医护（n=213）、兽医医护（n=211）或人类医护（n=162）家庭。
前瞻性横断面研究。对人类和宠物的样本进行体外培养。采用 mecA 聚合酶链反应鉴定金黄色葡萄球菌为甲氧西林敏感（MSSA）或 MRSA。脉冲场凝胶电泳和 spa 分型用于表征金黄色葡萄球菌和 MRSA 的相关性，并确定 USA 型。
人类 MSSA 和 MRSA 的患病率分别为 21.5%（126/586）和 5.63%（33/586），宠物 MSSA 和 MRSA 的患病率分别为 7.85%（46/586）和 3.41%（20/586）。不同家庭类型之间 MSSA 或 MRSA 的患病率没有差异。人与宠物的所有金黄色葡萄球菌分离株中，MRSA 的比例分别为 20.8%（33/159）和 30.3%（20/66）。在<1.0%（4/586）的家庭中，同一个人同时携带 MRSA 和宠物同时携带 MRSA。
医护人员和非医护人员家庭的 MSSA 或 MRSA 患病率没有差异。金黄色葡萄球菌定植的人与宠物同样可能定植 MRSA。人与宠物同时携带同一株 MRSA 的情况很少见。
