2009 年甲型 H1N1 流感大流行伴有神经学表现：病例系列研究。
Pandemic influenza A (H1N1) 2009 with neurological manifestations, a case series.
机构信息
Department of Medicine, Clínica Alemana de Santiago, Clínica Alemana School of Medicine, Universidad del Desarrollo, Santiago, Chile.
出版信息
Influenza Other Respir Viruses. 2010 May 1;4(3):117-20. doi: 10.1111/j.1750-2659.2010.00131.x.
OBJECTIVES
Describe a series of atypical presentations of pandemic influenza A (H1N1) 2009.
METHODS
Description of case series using hospital records.
RESULTS
Six patients aged 1 to 65 years with confirmed pandemic influenza A (H1N1) 2009 infection presented with neurological complications within 2 to 5 days after the first signs of influenza-like illness. All six were admitted with seizures or altered mental status. No abnormalities were found in brain scans or cerebral spinal fluid studies of any of the six. All were discharged without sequelae within days of admission.
CONCLUSIONS
This is only the second report of pandemic influenza presenting with neurological manifestations. Clinicians caring for patients when pandemic influenza is prevalent in their communities should maintain a high level of awareness of the potential atypical presentations with which this disease can appear.
目的
描述一系列甲型 H1N1 流感大流行的非典型表现。
方法
使用医院记录进行病例系列描述。
结果
6 名年龄在 1 至 65 岁之间的患者经确诊感染了甲型 H1N1 流感大流行病毒，在流感样疾病出现后 2 至 5 天内出现了神经系统并发症。这 6 名患者均因癫痫发作或意识状态改变而入院。对 6 名患者的脑部扫描或脑脊液研究均未发现任何异常。所有患者在入院后数天内均无后遗症出院。
结论
这是第二次有报告称甲型 H1N1 流感表现出神经系统症状。当流感大流行在其社区流行时，照顾患者的临床医生应高度警惕该病可能出现的不典型表现。
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