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造血干细胞移植后病毒感染的分子监测。

Molecular monitoring of viral infections after hematopoietic stem cell transplantation.

机构信息

Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Int J Hematol. 2010 May;91(4):596-601. doi: 10.1007/s12185-010-0570-4. Epub 2010 Apr 23.

DOI:10.1007/s12185-010-0570-4
PMID:20414752
Abstract

Viral infections are important complications after allogeneic hematopoietic stem cell transplantation. Viral load monitoring combined with preemptive antiviral therapy has become an established strategy for the management of CMV infections. This review discusses and summarizes information regarding viral load monitoring for EBV, human herpesvirus 6, and adenoviruses including virological and clinical aspects. Standardized assays are lacking for these viruses and additional studies are needed.

摘要

病毒感染是异基因造血干细胞移植后的重要并发症。病毒载量监测联合预防性抗病毒治疗已成为 CMV 感染管理的既定策略。本文讨论并总结了 EBV、人类疱疹病毒 6 和腺病毒病毒载量监测的相关信息，包括病毒学和临床方面。这些病毒缺乏标准化检测方法，需要进一步研究。

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Leukemia. 2010 Apr;24(4):706-14. doi: 10.1038/leu.2010.4. Epub 2010 Feb 11.
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Viral disease prevention after hematopoietic cell transplantation.造血细胞移植后的病毒病预防
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Transmission of chromosomally integrated human herpesvirsus 6 (HHV-6) variant A from a parent to children leading to misdiagnosis of active HHV-6 infection.
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Biology (Basel). 2022 Mar 30;11(4):536. doi: 10.3390/biology11040536.
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A Comprehensive Statistical Framework for Determination of Commutability, Accuracy, and Agreement in Clinical DNAemia Assays.用于确定临床 DNAemia 分析物可比性、准确性和一致性的综合统计框架。
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Acad Pathol. 2017 Jul 16;4:2374289517708309. doi: 10.1177/2374289517708309. eCollection 2017 Jan-Dec.
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Transpl Infect Dis. 2009 Dec;11(6):503-6. doi: 10.1111/j.1399-3062.2009.00430.x. Epub 2009 Jul 28.
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