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使用图像配准评估呼吸过程中的肺叶生物力学。

Evaluation of lobar biomechanics during respiration using image registration.

作者信息

Ding Kai, Yin Youbing, Cao Kunlin, Christensen Gary E, Lin Ching-Long, Hoffman Eric A, Reinhardt Joseph M

机构信息

Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, USA.

出版信息

Med Image Comput Comput Assist Interv. 2009;12(Pt 1):739-46. doi: 10.1007/978-3-642-04268-3_91.

Abstract

The human lungs are divided into five independent compartments called lobes. The lobar fissures separate the lung lobes. It is hypothesized that the lobar surfaces slide against each other during respiration. We propose a method to evaluate the sliding motion of the lobar surfaces during respiration using lobe-by-lobe mass-preserving non-rigid image registration. We measure lobar sliding by evaluating the relative displacement on both sides of the fissure. The results show a superior-inferior gradient in the magnitude of lobar sliding. We compare whole-lung-based registration accuracy to lobe-by-lobe registration accuracy using vessel bifurcation landmarks.

摘要

人的肺被分为五个独立的腔室,称为肺叶。叶间裂将肺叶分隔开。据推测,在呼吸过程中肺叶表面会相互滑动。我们提出了一种方法,通过逐叶的质量守恒非刚性图像配准来评估呼吸过程中肺叶表面的滑动运动。我们通过评估裂两侧的相对位移来测量肺叶滑动。结果显示肺叶滑动幅度存在上下梯度。我们使用血管分叉标志将基于全肺的配准精度与逐叶配准精度进行比较。

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