Prowle John R, Molan Maurice P, Hornsey Emma, Bellomo Rinaldo
Contrib Nephrol. 2010;165:329-336. doi: 10.1159/000313774. Epub 2010 Apr 20.
During critical illness, reductions in renal blood flow (RBF) are believed to be a major cause of kidney dysfunction, and therapy is often aimed at restoration of RBF. Despite this, our ability to measure RBF during critical illness has been limited by the invasiveness of the available techniques. Ciné Phase-Contrast Magnetic Resonance Imaging (CPC-MRI) represents an entirely noninvasive, contrast-free method of measuring blood flow with the potential of enabling the measurement of blood flow to major organs including the kidney. We have recently assessed the feasibility of measuring RBF by means of CPC-MRI in 2 critically ill patients with septic acute kidney injury and were able to compare such measurements to those obtained in a normal volunteer.
在危重症期间，肾血流量（RBF）的减少被认为是肾功能障碍的主要原因，治疗通常旨在恢复肾血流量。尽管如此，我们在危重症期间测量肾血流量的能力一直受到现有技术侵入性的限制。电影相位对比磁共振成像（CPC-MRI）代表了一种完全无创、无需造影剂的测量血流的方法，有可能实现对包括肾脏在内的主要器官的血流测量。我们最近评估了通过CPC-MRI测量2例脓毒症急性肾损伤危重症患者肾血流量的可行性，并能够将这些测量结果与正常志愿者的测量结果进行比较。
