Heck 反应在 1,3-和 1,2-不饱和衍生物中的应用，是一种通向分子复杂性的途径。

Dipartimento di Chimica Generale e Chimica Organica, Università di Torino, Via Pietro Giuria, Torino, Italy.

Molecules. 2010 Apr 13;15(4):2667-85. doi: 10.3390/molecules15042667.

This review is an overview of the last ten years' use of the Mizoroki-Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form pi-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures.

这篇综述概述了过去十年中 Mizoroki-Heck 偶联反应在 1,2-和 1,3-二烯中的应用。由于这两种体系在 Pd(0)偶联中都形成了 pi-烯丙基钯中间体，因此它们表现出特殊的化学行为。本文介绍了许多 1,2-二烯 Heck 反应的例子。1,2-二烯是重要的底物，因为它们的高反应性使它们成为合成具有生物相关性结构的有用构建块。