Programa de Pós-Graduação em Genética e Toxicologia, Universidade Luterana do Brasil, Aplicada, Av. Farroupilha, 8001 Bairro São José, Canoas, Rio Grande do Sul, Brazil.
Parasitol Res. 2010 Jun;107(1):243-8. doi: 10.1007/s00436-010-1878-y. Epub 2010 Apr 29.
The chemical composition of the essential oil obtained by hydrodistillation of the aerial parts of Piper amalago, Piper mikanianum, and Piper xylosteoides was elucidated by gas chromatography (GC) and GC/mass spectrometry analyses. P. mikanianum and P. xylosteoides essential oils presented phenylpropanoids as their main compounds (67.89% and 48.53%, respectively) whereas P. amalago was rich in monoterpene and sesquiterpene hydrocarbons (84.95%). The essential oils obtained were investigated for their effect on newly hatched larvae of the cattle tick, Rhipicephalus (Boophilus) microplus. The essential oil of P. mikanianum (LC(50) 2.33 microL/mL) was more active than that of P. xylosteoides (LC(50) 6.15 microL/mL) against the larvae, while the oil of P. amalago was inactive. These results suggest that phenylpropanoids, mainly apiol and safrole, are responsible for the acaricidal activity.
通过水蒸气蒸馏法从 Piper amalago、Piper mikanianum 和 Piper xylosteoides 的地上部分提取的精油的化学成分通过气相色谱(GC)和 GC/质谱分析得到了阐明。P. mikanianum 和 P. xylosteoides 的精油以苯丙素类化合物为主要成分(分别为 67.89%和 48.53%),而 P. amalago 则富含单萜和倍半萜烃(84.95%)。研究了所得精油对新孵化的牛蜱幼虫 Rhipicephalus(Boophilus)microplus 的影响。P. mikanianum 的精油(LC(50)2.33 μL/mL)比 P. xylosteoides 的精油(LC(50)6.15 μL/mL)对幼虫更有效,而 P. amalago 的精油则无效。这些结果表明,苯丙素类化合物,主要是藁本内酯和黄樟素,是杀蜱活性的原因。