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[科特迪瓦阿比让狂犬病暴露人群狂犬病疫苗治疗的依从性]

[Adherence to rabies vaccine treatment for people exposed to rabies in Abidjan (Côte d' Ivoire)].

作者信息

Tiembré Issaka, Aka-Kone Diloma Marie Brigitte, Konan Yao Eugène, Vroh Joseph Bénié Bi, Kouadio Daniel Ekra, N'cho Simplice Dagnan, Aka Joseph, Tagliante-Saracino Janine, Odehouri-Koudou Paul

机构信息

Département de Santé Publique et de Mèdecine Communautaire, Université de Cocody, bd de l'Université de Cocody 01, BP V 166 Abidjan, Côte d'Ivoire.

出版信息

Sante Publique. 2009 Nov-Dec;21(6):595-603.

PMID:20429229
Abstract

This descriptive retrospective study ran from August 2003 to December 2003 at the Rabies Center of the National Institute of Public Health in Abidjan. It covers subjects at risk of rabies transmission during 2004. Identification of participants in the study was made via a census of patients consulting the rabies clinic: a total of 533 subjects were included, predominantly male (54.6%), without gainful employment (57%), with an average age of 26.7 years. Those who lived outside the city of Abidjan accounted for 21.6%. In 88.2% of cases, they were exposed due to a bite. Dogs (90.8%) represented the main species responsible for this kind of exposure. Only 3.2% of these animals had a current valid rabies vaccine. The owner of the animal was not known in 71% of cases. The observance of the recommended immunization schedule for 4 doses was 53.1%. Of the 533 patients registered in the study, 46.9% had stopped treatment vaccine. Some factors have been identified as adversely affecting adherence, such as the vaccination treatment plan of 5 doses, exposure outside the city of Abidjan, unemployment, incurrence of superficial injuries, exposure from an animal bite and lack of immunization of the animal. The results show that the strategies against rabies must focus increasingly on the importance of adherence to treatment and education of the population vis-à-vis the risk of rabies.

摘要

这项描述性回顾性研究于2003年8月至2003年12月在阿比让国家公共卫生研究所狂犬病中心开展。研究涵盖了2004年有狂犬病传播风险的人群。通过对狂犬病诊所就诊患者进行普查来确定研究参与者:共纳入533名受试者,其中男性占主导(54.6%),无工作(57%),平均年龄26.7岁。居住在阿比让市以外的人占21.6%。在88.2%的病例中,他们是因被咬伤而暴露。狗(90.8%)是造成这种暴露的主要动物种类。这些动物中只有3.2%目前有有效的狂犬病疫苗。71%的病例中动物主人不明。4剂推荐免疫程序的依从率为53.1%。在研究登记的533名患者中,46.9%停止了疫苗治疗。已确定一些因素对依从性有不利影响,如5剂的疫苗接种治疗方案、在阿比让市以外暴露、失业、有浅表损伤、被动物咬伤暴露以及动物未免疫。结果表明,狂犬病防控策略必须越来越注重坚持治疗的重要性以及对民众进行狂犬病风险教育。

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