The Chinese University of Hong Kong, Hong Kong.
Aging Male. 2010 Jun;13(2):113-9. doi: 10.3109/13685530903440432.
Few prospective studies have been conducted to identify risk factors associated with lower urinary tract symptoms (LUTS). Our objective is to evaluate the dietary, lifestyle and medical risk factors of LUTS.
Data were collected from a large prospective cohort of elderly Chinese men in Hong Kong. Eight hundred seventy-one subjects provided response to a structured interviewer-administered questionnaire and physical examination at baseline and at 4-year follow-up. LUTS and depressive symptoms were assessed using International Prostate Symptom Score (IPSS) and Geriatric Depressive Symptom Scale (GDS).
The GDS score was independently associated with increased risk of having moderate to severe LUTS (odd ratios (OR) = 2.08; confidence interval (CI) = 1.28-3.40; Wald chi-square test = 9.52 and p = 0.023). A history of coronary heart disease was independently associated with increased risk of moderate to severe LUTS (OR = 1.65, CI: 1.05-2.59; Wald chi-square test = 4.74 and p = 0.029). Alcohol consumption of seven drinks or more per week was independently associated with increased risk of moderate to severe LUTS (OR = 2.51; CI: 1.32-4.79; Wald chi-square test = 8.01 and p = 0.018).
We have studied LUTS but not surgical BPH.
The results showed that medical and lifestyle factors may increase the risk of LUTS in Chinese elderly men.
很少有前瞻性研究确定与下尿路症状（LUTS）相关的风险因素。我们的目的是评估与 LUTS 相关的饮食、生活方式和医疗风险因素。
数据来自香港一项大型前瞻性老年华人男性队列研究。871 名受试者在基线和 4 年随访时提供了结构化访谈员管理的问卷调查和体检的回复。使用国际前列腺症状评分（IPSS）和老年抑郁症状量表（GDS）评估 LUTS 和抑郁症状。
GDS 评分与中度至重度 LUTS 的风险增加独立相关（比值比（OR）=2.08；置信区间（CI）=1.28-3.40；Wald chi-square 检验=9.52，p=0.023）。冠心病史与中度至重度 LUTS 的风险增加独立相关（OR=1.65，CI：1.05-2.59；Wald chi-square 检验=4.74，p=0.029）。每周饮酒 7 杯或以上与中度至重度 LUTS 的风险增加独立相关（OR=2.51；CI：1.32-4.79；Wald chi-square 检验=8.01，p=0.018）。
我们研究了 LUTS，但没有研究手术治疗的前列腺增生。
结果表明，医疗和生活方式因素可能会增加中国老年男性 LUTS 的风险。
