Iwase Takeshi, Jo Young-Joon, Tanaka Nobushige
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-9277, USA.
Cutan Ocul Toxicol. 2010 Jun;29(2):130-6. doi: 10.3109/15569521003745693.
To report the occurrence of transient ocular hypotony after indocyanine green (ICG)-assisted macular surgery for removal of the epiretinal membrane (ERM).
This was a retrospective review of 122 eyes of 118 patients who underwent vitrectomy for idiopathic ERM. The ICG staining technique was used in 71 eyes without fluid-air exchange (FAX) and in 15 eyes with FAX. Detailed eye examinations, including intraocular pressure (IOP) measurement, were performed before and after surgery.
We observed postoperative transient ocular hypotony with choroidal detachment in 8 of 71 eyes (11%) in the ICG (+)/FAX (-) group, and no ocular hypotony was seen in the ICG (+)/FAX (+) group (15 eyes) or in the ICG (-) group (36 eyes). The median best corrected visual acuity (BCVA) in the ICG(-)group was only significantly better than in the ICG (+)/FAX (-) with hypotony at 1 week after surgery (p = 0.046). However, there was no statistically significant difference in BCVA at 3 and 6 months after surgery among the groups (p > 0.05).
ICG staining of the internal limiting membrane (ILM) supports complete ERM removal because of enhanced visualization of the border between the ILM and the ERM. However, it should be cautioned that postoperative ocular hypotony may occur in some cases of ICG-assisted macular surgery. Therefore, informed consent with careful follow-up is required when ICG-assisted surgery is performed.
报告吲哚菁绿(ICG)辅助黄斑手术切除视网膜前膜(ERM)后发生短暂性眼压降低的情况。
这是一项对118例因特发性ERM接受玻璃体切除术的患者的122只眼进行的回顾性研究。71只眼采用ICG染色技术且未进行液气交换(FAX),15只眼采用ICG染色技术并进行了FAX。在手术前后进行了详细的眼部检查,包括眼压(IOP)测量。
我们观察到ICG(+)/FAX(-)组71只眼中有8只眼(11%)术后出现伴有脉络膜脱离的短暂性眼压降低,ICG(+)/FAX(+)组(15只眼)和ICG(-)组(36只眼)均未出现眼压降低。ICG(-)组术后1周时最佳矫正视力(BCVA)中位数仅显著优于出现眼压降低的ICG(+)/FAX(-)组(p = 0.046)。然而,术后3个月和6个月时各研究组间BCVA无统计学显著差异(p > 0.05)。
由于增强了内界膜(ILM)与ERM之间边界的可视化,ICG对ILM进行染色有助于完全切除ERM。然而,应注意在某些ICG辅助黄斑手术病例中可能会发生术后眼压降低。因此,进行ICG辅助手术时需要获得知情同意并进行仔细的随访。