协调不同的体内平衡过程。
Coordinating different homeostatic processes.
机构信息
Volen Center and Biology Department, Brandeis University, Waltham, MA 02454, USA.
出版信息
Neuron. 2010 Apr 29;66(2):161-3. doi: 10.1016/j.neuron.2010.04.022.
Abstract
In this issue of Neuron, Bergquist and colleagues study a rapid form of presynaptic homeostatic regulation at the Drosophila neuromuscular junction. They show that the K(+) channel genes shal and shaker are reciprocally regulated in the central nervous system and suggest a hierarchical organization of intrinsic and synaptic homeostatic regulatory processes.
摘要
本期《神经元》杂志上，Bergquist 及其同事研究了果蝇肌神经接点的一种快速突触前同型调节形式。他们发现，钾离子通道基因 shal 和 shaker 在中枢神经系统中呈相互调节关系，并提出了内在和突触同型调节过程的层级组织概念。
相似文献
1
Coordinating different homeostatic processes.协调不同的体内平衡过程。
Neuron. 2010 Apr 29;66(2):161-3. doi: 10.1016/j.neuron.2010.04.022.
2
A hierarchy of cell intrinsic and target-derived homeostatic signaling.细胞内在和靶源性稳态信号的层次结构。
Neuron. 2010 Apr 29;66(2):220-34. doi: 10.1016/j.neuron.2010.03.023.
3
Shal and shaker differential contribution to the K+ currents in the Drosophila mushroom body neurons.沙尔和振荡器对果蝇蕈形体神经元中钾离子电流的差异贡献。
J Neurosci. 2005 Mar 2;25(9):2348-58. doi: 10.1523/JNEUROSCI.4384-04.2005.
4
Shaker and Shal mediate transient calcium-independent potassium current in a Drosophila flight motoneuron.Shaker 和 Shal 在果蝇飞行运动神经元中介导瞬时钙非依赖性钾电流。
J Neurophysiol. 2009 Dec;102(6):3673-88. doi: 10.1152/jn.00693.2009. Epub 2009 Oct 14.
5
Endogenous Tagging Reveals Differential Regulation of Ca Channels at Single Active Zones during Presynaptic Homeostatic Potentiation and Depression.内源性标签揭示了在突触前稳态增强和抑制期间单个活性区钙通道的差异调节。
J Neurosci. 2019 Mar 27;39(13):2416-2429. doi: 10.1523/JNEUROSCI.3068-18.2019. Epub 2019 Jan 28.
6
Molecular underpinnings of motor pattern generation: differential targeting of shal and shaker in the pyloric motor system.运动模式生成的分子基础：幽门运动系统中shal和shaker的差异靶向作用
J Neurosci. 2000 Sep 1;20(17):6619-30. doi: 10.1523/JNEUROSCI.20-17-06619.2000.
7
Homeostatic synaptic depression is achieved through a regulated decrease in presynaptic calcium channel abundance.稳态突触抑制是通过突触前钙通道丰度的调节性降低来实现的。
Elife. 2015 Apr 17;4:e05473. doi: 10.7554/eLife.05473.
8
Homeostatic control of Drosophila neuromuscular junction function.果蝇神经肌肉接点功能的动态平衡控制。
Synapse. 2020 Jan;74(1):e22133. doi: 10.1002/syn.22133. Epub 2019 Oct 4.
9
Homeostatic control of presynaptic neurotransmitter release.突触前神经递质释放的稳态控制。
Annu Rev Physiol. 2015;77:251-70. doi: 10.1146/annurev-physiol-021014-071740. Epub 2014 Nov 5.
10
Cholinergic Synaptic Homeostasis Is Tuned by an NFAT-Mediated α7 nAChR-K4/Shal Coupled Regulatory System.胆碱能突触稳态由 NFAT 介导的 α7 nAChR-K4/Shal 偶联调节系统调控。
Cell Rep. 2020 Sep 8;32(10):108119. doi: 10.1016/j.celrep.2020.108119.
引用本文的文献
1
Reliability and robustness of oscillations in some slow-fast chaotic systems.一些快慢混沌系统中振荡的可靠性和鲁棒性。
Chaos. 2023 Oct 1;33(10). doi: 10.1063/5.0166846.
2
Homeostatic Plasticity Shapes the Retinal Response to Photoreceptor Degeneration.内稳可塑性塑造光感受器变性的视网膜反应。
Curr Biol. 2020 May 18;30(10):1916-1926.e3. doi: 10.1016/j.cub.2020.03.033. Epub 2020 Apr 2.
3
Circuit Stability to Perturbations Reveals Hidden Variability in the Balance of Intrinsic and Synaptic Conductances.电路稳定性对扰动的揭示揭示了内在和突触电导平衡中的隐藏可变性。
J Neurosci. 2020 Apr 15;40(16):3186-3202. doi: 10.1523/JNEUROSCI.0985-19.2020. Epub 2020 Mar 16.
4
Controlling neural network responsiveness: tradeoffs and constraints.控制神经网络的响应性：权衡与约束
Front Neuroeng. 2014 Apr 29;7:11. doi: 10.3389/fneng.2014.00011. eCollection 2014.
5
Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy.外显子组测序离子通道基因揭示了复杂的模式，混淆了癫痫患者的个人风险评估。
Cell. 2011 Jun 24;145(7):1036-48. doi: 10.1016/j.cell.2011.05.025.
本文引用的文献
1
A hierarchy of cell intrinsic and target-derived homeostatic signaling.细胞内在和靶源性稳态信号的层次结构。
Neuron. 2010 Apr 29;66(2):220-34. doi: 10.1016/j.neuron.2010.03.023.
2
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis.精神分裂症易感基因失调结合蛋白控制突触稳态。
Science. 2009 Nov 20;326(5956):1127-30. doi: 10.1126/science.1179685.
3
Homeostasis of intrinsic excitability in hippocampal neurones: dynamics and mechanism of the response to chronic depolarization.海马神经元内在兴奋性的稳态：对慢性去极化反应的动力学和机制。
J Physiol. 2010 Jan 1;588(Pt 1):157-70. doi: 10.1113/jphysiol.2009.181024. Epub 2009 Nov 16.
4
Network homeostasis: a matter of coordination.网络稳态：协调的问题。
Curr Opin Neurobiol. 2009 Apr;19(2):168-73. doi: 10.1016/j.conb.2009.05.012. Epub 2009 Jun 18.
5
A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels.一个由Eph受体、ephexin、Cdc42和CaV2.1钙通道组成的突触前稳态信号系统。
Neuron. 2009 Feb 26;61(4):556-69. doi: 10.1016/j.neuron.2008.12.028.
6
The self-tuning neuron: synaptic scaling of excitatory synapses.自调节神经元：兴奋性突触的突触缩放
Cell. 2008 Oct 31;135(3):422-35. doi: 10.1016/j.cell.2008.10.008.
7
Activity and neuromodulatory input contribute to the recovery of rhythmic output after decentralization in a central pattern generator.在中枢模式发生器中，活动和神经调节输入有助于去中枢化后节律性输出的恢复。
J Neurophysiol. 2009 Jan;101(1):372-86. doi: 10.1152/jn.01290.2007. Epub 2008 Jul 2.
8
Homeostatic regulation of intrinsic excitability and synaptic transmission in a developing visual circuit.发育中的视觉回路中内在兴奋性和突触传递的稳态调节。
J Neurosci. 2007 Aug 1;27(31):8268-77. doi: 10.1523/JNEUROSCI.1738-07.2007.
9
Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis.突触稳态快速诱导和持续表达的潜在机制。
Neuron. 2006 Nov 22;52(4):663-77. doi: 10.1016/j.neuron.2006.09.029.
10
Variability, compensation and homeostasis in neuron and network function.神经元及网络功能中的变异性、代偿与内稳态
Nat Rev Neurosci. 2006 Jul;7(7):563-74. doi: 10.1038/nrn1949.
Zotero 插件