Cascade Elisa F, Kalali Amir H, Thase Michael E
Ms. Cascade is Vice President, Strategic Research and Safety, Quintiles Inc., Falls Church, Virginia.
Psychiatry (Edgmont). 2007 Dec;4(12):25-8.
We investigated antidepressant prescriptions and reasons for use. According to our data, the top 10 molecules represent approximately 95% of total antidepressant prescriptions for both primary care physicians (PCPs) and psychiatrists. The primary difference between PCPs and psychiatrists was the increased use of buproprion and tricyclics/tetracyclics by psychiatrists. The selective serotonin reuptake inhibitors (SSRIs) and other newer antidepressants such as venlafaxine (Effexor) and buproprion (Wellbutrin) are used to treat depression, anxiety, and bipolar disorders. The noted exception is duloxetine (Cymbalta), which looks like a blend between the newer agents and the tricyclics where there is use beyond the traditional central nervous system (CNS) disorders into pain and migraine.
我们调查了抗抑郁药的处方情况及用药原因。根据我们的数据，对于初级保健医生（PCP）和精神科医生而言，排名前十的药物分子约占抗抑郁药总处方量的95%。PCP和精神科医生之间的主要差异在于，精神科医生增加了安非他酮以及三环类/四环类药物的使用。选择性5-羟色胺再摄取抑制剂（SSRI）以及其他新型抗抑郁药，如文拉法辛（怡诺思）和安非他酮（安非他酮），用于治疗抑郁症、焦虑症和双相情感障碍。值得注意的例外是度洛西汀（欣百达），它似乎是新型药物和三环类药物的混合体，其应用范围超越了传统的中枢神经系统（CNS）疾病，还用于疼痛和偏头痛。
