洪都拉斯女性性工作者中的人类免疫缺陷病毒感染与梅毒

Human immunodeficiency virus infection and syphilis in Hondurian female prostitutes.

作者信息

Venegas V S, Madrid J P, Lorenzana I, Grillner L, Cosenza H, Bygdeman S

机构信息

Department of Microbiology, National Autonomous University of Honduras, Tegucigalpa DC.

出版信息

Int J STD AIDS. 1991 Mar-Apr;2(2):110-3. doi: 10.1177/095646249100200206.

DOI:10.1177/095646249100200206

PMID:2043701

Abstract

The seroprevalence of human immunodeficiency virus (HIV) infection and syphilis was investigated in 181 female prostitutes in Tegucigalpa, Honduras. One particle agglutination test and two enzyme immunoassays, as well as one immunofluorescence test were used for the screening of HIV antibodies. Confirmation of positive results by the screening tests was carried out by Western blot. The prevalence of HIV seropositivity was 4% (8 women). Specific treponemal antibodies were found in 50% (90/181) of the prostitutes as judged by Treponema pallidum haemagglutination assay (TPHA) and/or fluorescent treponemal antibody-absorption (FTA-ABSIgG) test. As estimated by the positivity of any or both non-treponemal tests (VDRL and RPR), a total of 31 (17%) out of the 181 women had active syphilis. A good correlation was found between the results obtained by TPHA and FTA-ABSIgG. IgM antibodies were found in 72% of sera positive by TPHA and/or FTA-ABSIgG. Four out of the 181 women were found to have antibodies to both HIV and Treponema pallidum.

摘要

在洪都拉斯特古西加尔巴的181名女性性工作者中，对人类免疫缺陷病毒（HIV）感染和梅毒的血清流行率进行了调查。采用一种颗粒凝集试验、两种酶免疫测定法以及一种免疫荧光试验来筛查HIV抗体。筛查试验呈阳性结果的确认通过蛋白质印迹法进行。HIV血清阳性率为4%（8名女性）。根据梅毒螺旋体血凝试验（TPHA）和/或荧光梅毒螺旋体抗体吸收试验（FTA-ABSIgG）判断，50%（90/181）的性工作者中发现了特异性梅毒螺旋体抗体。根据任一非梅毒螺旋体试验（VDRL和RPR）或两者的阳性结果估计，181名女性中共有31名（17%）患有活动性梅毒。TPHA和FTA-ABSIgG所获结果之间存在良好相关性。在TPHA和/或FTA-ABSIgG呈阳性的血清中，72%发现有IgM抗体。181名女性中有4名被发现同时具有抗HIV和梅毒螺旋体的抗体。