First Department of Pediatrics, P and A Kyriakou Children's Hospital, 11527 Athens, Greece.
Eur J Pediatr. 2010 Sep;169(9):1143-5. doi: 10.1007/s00431-010-1162-2. Epub 2010 May 4.
Bovine tuberculosis is a zoonotic disease, and although its incidence has dramatically decreased in developed countries where effective control measures are applied, it still remains a potential health hazard in the developing world. Tuberculosis of the oral cavity is extremely rare and is usually secondary to pulmonary involvement. We present the unusual case of an immunocompetent 6-year-old child residing in an urban area with primary oral tuberculosis due to Mycobacterium bovis, which was confirmed by the application of a molecular genetic approach. M. bovis belongs to Mycobacterium tuberculosis complex which comprises species with close genetic relationship, and for this reason, the use of new molecular techniques is a useful tool for the differentiation at species level of the closely related members of this complex.
牛型结核病是一种人畜共患疾病，尽管在发达国家采取了有效的控制措施，其发病率已经大幅下降，但在发展中国家仍然是一个潜在的健康危害。口腔结核极为罕见，通常是肺部受累的继发症。我们报告了一例不常见的病例，一名居住在城市地区的免疫功能正常的 6 岁儿童，由于感染牛分枝杆菌而患有原发性口腔结核，这通过分子遗传方法得到了证实。牛分枝杆菌属于结核分枝杆菌复合群，该复合群包括具有密切遗传关系的物种，因此，新的分子技术的使用是区分该复合群中密切相关成员的物种水平的有用工具。
