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初始体重下降率与肥胖治疗长期成功之间的关系:是慢工出细活吗?

The association between rate of initial weight loss and long-term success in obesity treatment: does slow and steady win the race?

机构信息

Department of Clinical and Health Psychology, University of Florida, PO Box 100165, Gainesville, FL 32610-0165, USA.

出版信息

Int J Behav Med. 2010 Sep;17(3):161-7. doi: 10.1007/s12529-010-9092-y.

Abstract

BACKGROUND

Controversy exists regarding the optimal rate of weight loss for long-term weight management success.

PURPOSE

This study examined whether gradual initial weight loss was associated with greater long-term weight reduction than rapid initial loss.

METHODS

Groups were drawn from participants in the TOURS trial, which included a sample of middle-aged (mean = 59.3 years) obese women (mean BMI = 36.8) who received a 6-month lifestyle intervention followed by a 1-year extended care program. Participants were encouraged to reduce caloric intake to achieve weight losses of 0.45 kg/week. Groups were categorized as "FAST" (> or =0.68 kg/week, n = 69), "MODERATE" (> or =0.23 and <0.68 kg/week, n = 104), and "SLOW" (<0.23 kg/week, n = 89) based on rate of weight loss during first month of treatment.

RESULTS

The FAST, MODERATE, and SLOW groups differed significantly in mean weight changes at 6 months (-13.5, -8.9, and -5.1 kg, respectively, ps < 0.001), and the FAST and SLOW groups differed significantly at 18 months (-10.9, -7.1, and -3.7 kg, respectively, ps < 0.001). No significant group differences were found in weight regain between 6 and 18 months (2.6, 1.8, and 1.3 kg, respectively, ps < 0.9). The FAST and MODERATE groups were 5.1 and 2.7 times more likely to achieve 10% weight losses at 18 months than the SLOW group.

CONCLUSION

Collectively, findings indicate both short- and long-term advantages to fast initial weight loss. Fast weight losers obtained greater weight reduction and long-term maintenance, and were not more susceptible to weight regain than gradual weight losers.

摘要

背景

长期体重管理成功的最佳减重速度存在争议。

目的

本研究旨在探讨初始体重缓慢下降是否比快速下降更有利于长期体重减轻。

方法

研究对象来自 TOURS 试验的参与者,包括中年肥胖女性(平均年龄=59.3 岁,平均 BMI=36.8),她们接受了为期 6 个月的生活方式干预,随后进行了为期 1 年的扩展护理项目。参与者被鼓励减少热量摄入,以实现每周减少 0.45 公斤的体重。根据治疗第一个月的减重速度,将参与者分为“快速”(>或=0.68 公斤/周,n=69)、“中度”(>或=0.23 且<0.68 公斤/周,n=104)和“缓慢”(<0.23 公斤/周,n=89)三组。

结果

快速、中度和缓慢三组在 6 个月时的平均体重变化差异显著(分别为-13.5、-8.9 和-5.1 公斤,p 值均<0.001),且在 18 个月时快速和缓慢两组差异显著(分别为-10.9、-7.1 和-3.7 公斤,p 值均<0.001)。6 个月至 18 个月期间,体重反弹没有显著的组间差异(分别为 2.6、1.8 和 1.3 公斤,p 值均<0.9)。与缓慢组相比,快速和中度组在 18 个月时达到 10%体重减轻的可能性分别高 5.1 倍和 2.7 倍。

结论

总的来说,快速初始体重下降既具有短期优势,也具有长期优势。快速减肥者获得了更大的体重减轻和长期维持,并且体重反弹的可能性并不高于缓慢减肥者。

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