Yamaguchi Toru, Sugimoto Toshitsugu
Internal Medicine 1, Faculty of Medicine, Shimane University.
Clin Calcium. 2010 May;20(5):637-44.
Secondary osteoporosis is caused by various disorders, metabolic derangements, and drug administration, whose elimination as a cause for osteoporosis is necessary before establishing the diagnosis of primary osteoporosis. The underlying diseases or conditions are diversified, including those related to endocrine, nutrition, rheumatism, immobility, medicine, hematology, and congenital one. Among them, osteoporosis induced by steroid administration and that accompanied by diabetes mellitus are most frequently observed. They exhibit high fracture risks based on deteriorated bone quality rather than reduced bone mass.
继发性骨质疏松症由多种疾病、代谢紊乱及药物使用引起，在诊断原发性骨质疏松症之前，必须消除这些作为骨质疏松症病因的因素。潜在的疾病或状况多种多样，包括与内分泌、营养、风湿、不动、药物、血液学及先天性因素相关的疾病。其中，最常观察到的是由使用类固醇引起的骨质疏松症和伴有糖尿病的骨质疏松症。它们由于骨质恶化而非骨量减少而具有较高的骨折风险。
