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墨西哥韦拉克鲁斯州孕妇脂肪组织中的有机氯农药水平。

Organochlorine pesticide levels in adipose tissue of pregnant women in Veracruz, Mexico.

机构信息

Biomedical Sciences Doctor Study, University of Veracruz, Xalapa, Mexico.

出版信息

Bull Environ Contam Toxicol. 2010 Jun;84(6):652-6. doi: 10.1007/s00128-010-0028-7. Epub 2010 May 7.

Abstract

DDT and Lindane (gamma-HCH) which were used until 1999 in Mexico, have provided great benefits in the combat of vectors that spread infection-borne diseases and in agriculture for crop protection. The persistence in the environment and their accumulative properties results in bioconcentration in lipid rich tissues of the human body that reflect the extent of environmental pollution. Human adipose tissue samples were taken during 2009 from abdominal cavities of 69 pregnant women by cesarean surgery and from 34 samples of control donors by autopsy in Veracruz State. The samples were analyzed by gas chromatography with ECD. The results of mean levels (mg/kg on fat basis) were higher in controls compared to pregnant women beta-HCH 0.064 vs 0.027; pp'DDE 1.187 vs. 0.745; op'DDT 0.016 vs. 0.011; pp'DDT 0.117 vs. 0.099 and Sigma-DDT 1.337 vs. 0.854. The pregnant women group was divided according to age: up to 20, 20-30, and more than 30 years, and presented an increase for the more persistent pesticides with age in terms of mean concentrations and a more pronounced higher correlation in medians levels. Pairing Body Mass Index to organochlorine pesticide mean levels revealed no correlation between these factors in pregnant women.

摘要

滴滴涕和林丹(γ-六氯环己烷)曾在 1999 年以前在墨西哥被使用,它们在防治传播感染性疾病的病媒和农业作物保护方面带来了巨大的益处。这些物质在环境中的持久性及其积累特性导致它们在富含脂肪的人体组织中发生生物浓缩,反映出环境污染的程度。2009 年,在韦拉克鲁斯州,通过剖腹产手术从 69 名孕妇的腹腔中以及通过尸检从 34 名对照供体中采集了人体脂肪组织样本。这些样本通过气相色谱法和电子捕获检测进行了分析。结果显示,对照组的平均水平(脂肪基础上的毫克/千克)高于孕妇组:β-六氯环己烷为 0.064 比 0.027;p,p'-滴滴伊为 1.187 比 0.745;o,p'-滴滴涕为 0.016 比 0.011;p,p'-滴滴涕为 0.117 比 0.099;Σ滴滴涕为 1.337 比 0.854。根据年龄将孕妇组分为三组:20 岁以下、20-30 岁和 30 岁以上,随着年龄的增长,持久性更强的农药的平均浓度呈上升趋势,中位数水平的相关性更为显著。将体重指数与有机氯农药的平均水平进行配对,并未发现孕妇的这些因素之间存在相关性。

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