Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 91980 Boca del Río, Ver, Mexico.
Bull Environ Contam Toxicol. 2011 Nov;87(5):539-44. doi: 10.1007/s00128-011-0341-9. Epub 2011 Jun 18.
The objective of the present study was to monitor the levels of organochlorine pesticides HCB, α-β-γ-HCH, pp'DDE, op'DDT and pp'DDT in 150 adipose tissue samples of Veracruz, Mexico inhabitants. In analyzed samples, the following pesticides were detected: p,p'-DDE in 100% of the samples at mean 1.643 mg/kg; p,p'-DDT in 99.3.% of the samples at mean 0.227 mg/kg; β-HCH in 97.3% of the samples at mean 0.063 mg/kg; and op'DDT in 93.3% of the samples at mean 0.022 mg/kg. Comparing mean, median and geometric mean concentrations of organochlorine pesticides shows a decrease in values from mean to median and to geometric mean which points out a prevalence of lower concentrations among the total samples and the existence of occasional cases of extreme exposure expressed in range values. The pooled samples divided according to sex, showed only significant differences of pp'DDE median concentrations between sexes. The other organochlorine pesticides indicated no statistical differences between sexes, including the pp'DDE/pp'DDT ratio. The samples grouped according to age, showed that the third tertile was more contaminated for both sexes, indicating age as a positively associated factor with organochlorine pesticide levels in adipose tissue of Veracruz inhabitants. Comparing organochlorine pesticide levels between 2008 and 2010 years, a decreased tendency for β-HCH, pp'DDE, Σ-DDT and pp'DDE/pp'DDT ratio levels was observed.
本研究的目的是监测 150 名墨西哥韦拉克鲁斯州居民的 150 个脂肪组织样本中有机氯农药 HCB、α-β-γ-HCH、pp'DDE、op'DDT 和 pp'DDT 的水平。在所分析的样本中，检测到以下农药：p,p'-DDE 在 100%的样本中平均浓度为 1.643mg/kg；p,p'-DDT 在 99.3%的样本中平均浓度为 0.227mg/kg；β-HCH 在 97.3%的样本中平均浓度为 0.063mg/kg；op'DDT 在 93.3%的样本中平均浓度为 0.022mg/kg。比较有机氯农药的平均值、中位数和几何平均值浓度表明，从平均值到中位数和几何平均值，值呈下降趋势，这表明在总样本中存在较低浓度的普遍情况，并且存在偶尔出现的极端暴露情况，表现为范围值。根据性别对 pooled 样本进行分组，仅发现男女之间 pp'DDE 中位数浓度存在显著差异。其他有机氯农药在性别之间没有统计学差异，包括 pp'DDE/pp'DDT 比值。根据年龄对样本进行分组，发现两性的第三 tertile 更受污染，表明年龄是与韦拉克鲁斯州居民脂肪组织中有机氯农药水平呈正相关的因素。比较 2008 年和 2010 年有机氯农药水平，观察到β-HCH、pp'DDE、Σ-DDT 和 pp'DDE/pp'DDT 比值水平呈下降趋势。
