Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 91980 Boca del Río, Mexico.
Bull Environ Contam Toxicol. 2012 Feb;88(2):296-301. doi: 10.1007/s00128-011-0438-1. Epub 2011 Oct 29.
The objective of this study was to determine the levels of organochlorine pesticides HCB, α-β-γ-HCH, pp'DDE, op'DDT and pp'DDT in adipose tissue of females living in Puebla, Mexico. Organochlorine pesticides were analyzed in 75 abdominal adipose tissue samples taken during 2010 by autopsy at the Forensic Services of Puebla. The results were expressed as mg/kg on fat basis. In analyzed samples the following pesticides were detected: p,p'-DDE in 100% of samples at mean 1.464 mg/kg; p,p'-DDT in 96.0.% of samples at mean 0.105 mg/kg; op'DDT in 89.3% of monitored samples at mean 0.025 mg/kg and β-HCH in 94.7% of the samples at mean 0.108 mg/kg. To show if organochlorine pesticide levels in monitored female's adipose tissues are age dependant, the group was divided in three ages ranges (13-26, 26-57 and 57-96 years). The mean and median levels of all organochlorine pesticides increase significantly (p < 0.05) from the first to second and from the first to third group. At the same time, the increase of mean and medians levels from the second to third group were not statistically significant (p > 0.05). The present results compared to previous ones from 2008 indicates an increase in the concentrations during the 2010 study, but only the differences for pp'DDE and op'DDT were statistically significant. The 2010 group of females was older compared to the 2008 group. The presence of organochlorine pesticide residues is still observed, indicating uniform and permanent exposure to the pesticides by Puebla inhabitants.
本研究的目的是确定居住在墨西哥普埃布拉的女性脂肪组织中有机氯农药 HCB、α-β-γ-六氯环己烷、pp'DDE、op'DDT 和 pp'DDT 的水平。2010 年，在法医服务处进行尸检时，从 75 名女性的腹部脂肪组织中抽取了有机氯农药样本。结果以脂肪为基础表示为 mg/kg。在所分析的样本中检测到以下农药：p,p'-DDE 在 100%的样本中，平均浓度为 1.464mg/kg；p,p'-DDT 在 96.0%的样本中，平均浓度为 0.105mg/kg；op'DDT 在 89.3%的监测样本中，平均浓度为 0.025mg/kg，β-HCH 在 94.7%的样本中，平均浓度为 0.108mg/kg。为了表明监测女性脂肪组织中有机氯农药水平是否与年龄有关，将该组分为三个年龄范围（13-26、26-57 和 57-96 岁）。所有有机氯农药的平均和中位数水平从第一组到第二组和从第一组到第三组均显著增加（p<0.05）。同时，第二组到第三组的平均和中位数水平的增加没有统计学意义（p>0.05）。与 2008 年的先前结果相比，本研究 2010 年的浓度有所增加，但只有 pp'DDE 和 op'DDT 的差异具有统计学意义。2010 年的女性组比 2008 年的女性组年龄更大。有机氯农药残留仍然存在，表明普埃布拉居民仍在持续接触这些农药。
