Parafianowicz Katarzyna, Sicińska Justyna, Moran Anna, Szumański Jakub, Staniszewski Krzysztof, Rudnicka Lidia, Kokoszka Andrzej
Fundacja "Serce Dziecka", Warszawa.
Psychiatr Pol. 2010 Jan-Feb;44(1):119-26.
There are some reports about the relatively frequent occurrence of depression in the case of psoriasis and some hypothesis about interactions between those two diseases. However there are no studies verifying those hypothesis based on reliable structured psychiatric interviews according to the current diagnostic criteria of mental disorders. The aim of the study was to compare the frequency of depression in patients suffering from psoriasis and from other chronic skin diseases with the use of a structured questionnaire for the diagnosis of the main mental disorders Mini International Neuropsychiatric Interview.
32 consecutive outpatients (9 males and 23 females), age M = 43.9 with psoriasis were examined by a team of dermatologists, psychiatrists and a psychologist using a standard set of methods. In addition, 32 patients with other chronically occurring skin diseases, including 11 males and 21 females, age M = 31.6, were also examined and formed the control group. RESULTS; The point prevalence of mental disorders was significantly higher in the psoriatic group--20 (62.5%) versus 5 (15.62%) in the control group (p < 0.001). In all of the cases, affective disorders were diagnosed. Mild anxiety disorders were additionally found in 10 psoriatic patients (31.25%) and in 2 controls (6.25%) (p < 0.001). The level of depression was much higher in the study group than in the control group, both in the Beck Depression Inventory (M = 15.28, SD = 8.72 versus M = 8.13, SD = 6.31, p < 0.001 respectively) and in the Hamilton Rating Scale for Depression (M = 9.63, SD = 5.71 versus M = 5.09, SD = 4.26, p < 0.001 respectively). The neurotic symptoms measured by the Symptoms Check List-II by Aleksandrowicz were also significantly more intense in the psoriatic group (M = 54.37; SD = 40.99) than in the control group (M = 35.28; SD 23.96) (F = 8.55, p < 0.005).
The results imply the need for the careful examination of the mental state of patients with psoriasis in order to offer and provide treatment of any concomitant psychiatric conditions.
有一些报告指出银屑病患者中抑郁症的发生率相对较高，并且存在关于这两种疾病之间相互作用的一些假说。然而，尚无基于可靠的结构化精神科访谈、依据当前精神障碍诊断标准来验证这些假说的研究。本研究的目的是使用用于诊断主要精神障碍的结构化问卷——简明国际神经精神访谈，比较银屑病患者与其他慢性皮肤病患者中抑郁症的发生率。
一组皮肤科医生、精神科医生和一名心理学家使用一套标准方法，对32名连续就诊的门诊银屑病患者（9名男性和23名女性，平均年龄M = 43.9岁）进行了检查。此外，还对32名患有其他慢性皮肤病的患者（包括11名男性和21名女性，平均年龄M = 31.6岁）进行了检查，这些患者组成了对照组。结果：银屑病组精神障碍的时点患病率显著高于对照组——分别为20例（62.5%）和5例（15.62%）（p < 0.001）。所有病例均被诊断为情感障碍。另外，在10例银屑病患者（31.25%）和2例对照组患者（6.25%）中发现了轻度焦虑障碍（p < 0.001）。无论是在贝克抑郁量表（分别为M = 15.28，SD = 8.72与M = 8.13，SD = 6.31，p < 0.001）还是在汉密尔顿抑郁评定量表（分别为M = 9.63，SD = 5.71与M = 5.09，SD = 4.26，p < 0.001）中，研究组的抑郁水平均显著高于对照组。由亚历山德罗维茨症状自评量表-II测量的神经症症状在银屑病组（M = 54.37；SD = 40.99）中也明显比对照组（M = 35.28；SD 23.96）更强烈（F = 8.55，p < 0.005）。
研究结果表明需要仔细检查银屑病患者的精神状态，以便对任何伴发的精神疾病进行诊断和治疗。
