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银屑病患者的临床严重程度、心理困扰和精神病理特征的多变量分析。

A multivariate analysis of clinical severity, psychological distress and psychopathological traits in psoriatic patients.

机构信息

University Department of Dermatology and Venereology, Sestre milosrdnice University Hospital, 10000 Zagreb, Croatia.

出版信息

Acta Derm Venereol. 2010 May;90(3):251-6. doi: 10.2340/00015555-0838.

DOI:10.2340/00015555-0838
PMID:20526541
Abstract

Psoriasis is a chronic skin disease associated with problems in body image and self-esteem and feelings of stigma and shame. The aim of this study was to analyse the clinical extent of psoriasis and its association with psychological distress, and to compare the psychopathological traits in early-onset (type I: age of onset < 40 years) vs. late-onset (type II: age of onset > 40 years) psoriasis. A total of 140 patients participated in the study; 70 patients with confirmed diagnosis of psoriasis vulgaris and 70 patients as a comparative group. A battery of psychological instruments was used together with an Inventory of life stress events. The severity of psoriasis was assessed by standardized Psoriasis Area and Severity Index measure. The Psoriasis Life Stress Inventory showed the significant correlation with clinical extent of psoriasis and other measures of psychological distress. Patients with late-onset psoriasis had more prominent symptoms of depression compared with the group with early-onset psoriasis and the comparative group. The results of the Minnesota Multiphasic Personality Inventory-201 for the patient group with late-onset psoriasis showed a specific configuration of neurotic triad.

摘要

银屑病是一种慢性皮肤病,与身体形象和自尊问题以及耻辱感和羞耻感有关。本研究的目的是分析银屑病的临床严重程度及其与心理困扰的关系,并比较早发性(I 型:发病年龄<40 岁)和晚发性(II 型:发病年龄>40 岁)银屑病的心理病理特征。共有 140 名患者参与了这项研究;70 名患者被确诊为寻常型银屑病,70 名患者作为对照组。使用了一系列心理工具,以及生活压力事件清单。银屑病严重程度采用标准化的银屑病面积和严重程度指数评估。银屑病生活压力量表与银屑病的临床严重程度以及其他心理困扰测量指标显著相关。与早发性银屑病组和对照组相比,晚发性银屑病患者的抑郁症状更为明显。晚发性银屑病患者的明尼苏达多相人格问卷-201 测试结果显示出神经质三联征的特定配置。

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