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[Research on substances with antiviral activity. VIII. Benzindanoncarboxylic acids].

作者信息

Cavrini V, Gatti R, Andreani A, Giovanninetti G, Franchi L, Nanetti A

出版信息

Farmaco Sci. 1978 Feb;33(2):92-8.

PMID:204512
Abstract

New derivatives (esters, amides, nitriles, amidines, thiosemicarbazones and guanylhydrazones) of 1H-benz[e]indene-2,3-dihydro-5-methyl-1-oxo-3-carboxylic acid and 1H-benz[e]indene-2,3-dihydro-7-methyl-3-oxo-1-carboxylic acid were prepared and tested for antiviral activities in vitro against vaccinia virus, HID stock and parainfluenza type 3 virus, HA-I/CR-8 stock. Four compounds (II g), (II i), (III b), (III g), showed weak activity in vitro against vaccinia virus.

摘要

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