Andreani A, Cavrini V, Giovanninetti G, Mannini Palenzona A, Franchi L
Farmaco Sci. 1975 Jun;30(6):440-8.
Thiosemicarbazones and amidinohydrazones of N-substituted 2-chloroindole-3-aldehydes were synthesized and investigated for antiviral activity against RNA virus (parainfluenza type 3, HA-I/CR-8 stock) and DNA virus (vaccinia virus, HID stock). The thiosemicarbazones of 1-(o,m,p,-chlorobenzoyl)-2-chloroindole-3-aldehydes were more active than methisazone against vaccinia virus.
合成了N-取代的2-氯吲哚-3-醛的硫代氨基脲和脒腙，并研究了它们对RNA病毒（3型副流感病毒，HA-I/CR-8毒株）和DNA病毒（痘苗病毒，HID毒株）的抗病毒活性。1-(邻、间、对氯苯甲酰基)-2-氯吲哚-3-醛的硫代氨基脲对痘苗病毒的活性比甲吲噻腙更高。
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