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[Substances having antiviral activity. IX. Synthesis and antiviral activity of 1-acyl-2-halo-3-formylindole thiosemicarbazones].

作者信息

Andreani A, Bonazzi D, Cavrini V, Gatti R, Giovanninetti G, Rambaldi M, Franchi L, Nanetti A, Guarda M A

出版信息

Farmaco Sci. 1978 Oct;33(10):754-60.

PMID:217729
Abstract

Some thiosemicarbazones of 1-acyl-2-chloro-3-formylindoles were synthesized and investigated for antiviral activity against vaccinia virus, HID stock and parainfluenza virus type 3 HA-I/CR-8 stock. Evidence of antiviral activity was found only against vaccinia virus, and was particular significant with the m-substituted 1-benzoyl-2-chloro-3-formylindoles. The first results of 2-substitution of chlorine by bromine in the indole skeleton, are reported.

摘要

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Farmaco Sci. 1978 Oct;33(10):754-60.
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