功能化碳纳米管在潜在医学应用中的研究进展
Functionalized carbon nanotubes for potential medicinal applications.
机构信息
School of Pharmaceutical Sciences, Shandong University, Jinan, 250100, China.
出版信息
Drug Discov Today. 2010 Jun;15(11-12):428-35. doi: 10.1016/j.drudis.2010.04.005. Epub 2010 May 6.
Abstract
Functionalized carbon nanotubes display unique properties that enable a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity. High aspect ratio, unique optical property and the likeness as small molecule make carbon nanotubes an unusual allotrope of element carbon. After functionalization, carbon nanotubes display potentials for a variety of medicinal applications, including the diagnosis and treatment of cancer, infectious diseases and central nervous system disorders, and applications in tissue engineering. These potential applications are particularly encouraged by their ability to penetrate biological membranes and relatively low toxicity.
摘要
功能化碳纳米管具有独特的性质，使其在医学领域有多种应用，包括癌症、传染病和中枢神经系统疾病的诊断和治疗，以及在组织工程中的应用。其能够穿透生物膜和相对较低的毒性，这使得这些潜在应用尤其受到鼓励。高纵横比、独特的光学特性和小分子的相似性使碳纳米管成为碳元素的一种不寻常的同素异形体。经过功能化处理后，碳纳米管在多种医学应用中具有潜力，包括癌症、传染病和中枢神经系统疾病的诊断和治疗，以及在组织工程中的应用。其能够穿透生物膜和相对较低的毒性，这使得这些潜在应用尤其受到鼓励。
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