International Agency for Research on Cancer, Descriptive Epidemiology Production Group, Lyon, France.
Cancer Epidemiol. 2010 Aug;34(4):501-6. doi: 10.1016/j.canep.2010.04.012. Epub 2010 May 10.
Population-based cancer registries (PBCRs) are instruments to provide cancer incidence to promote cancer control and etiological research. A setting of mandatory (standard) variables is routinely collected for patient and tumor. One recommended variable is tumor stage, which supplies information on disease status and is an essential prognostic factor. However, it is not considered as necessary information to be collected by the PBCR. There are studies showing the value of stage as a prognostic variable to evaluate survival, socio-economic status, race and ethnics differences. Our aim is to analyze the feasibility of PBCRs in abstracting TNM for oral cavity and oropharynx. These topographies were selected due to the clinical accessibility of stage tumors by visual inspection and palpation. About 23% of the PBCRs who contributed to CI5-IX indicated their collection of TNM stage for all cancer sites. We analyzed 23,935 cases of oral cavity (OCC) and oropharynx cancer (OPC) from 13 PBCRs. Complete TNM stage for OCC was 52.7% for males and 47.6% for females; for OPC, it was 56% in both genders. Incomplete stage on OCC and OPC ranged from 22 to 25%. Missing was about 18-27% (most common in oral cavity). Missing stage was significantly higher in males for OCC aged > or =70 years, OR 1,64 (1.39-1.94). Our results demonstrate that OPC tend to have more stage, when compared with OCC. Even if it can be diagnosed by visual inspection, these results highlight the fact that information on stage can be a reliable indicator of access to healthcare and diagnosis awareness. Our results demonstrate that is feasible for PBCR to collect stage, although improving completeness of this information needs further technical training and international recommendation to adopt TNM stage as a standard variable for the PBCRs.
基于人群的癌症登记处（PBCR）是提供癌症发病率以促进癌症控制和病因学研究的工具。通常会为患者和肿瘤收集强制性（标准）变量设置。推荐的变量之一是肿瘤分期，它提供了有关疾病状态的信息，是一个重要的预后因素。然而，它并不被认为是 PBCR 必须收集的信息。有研究表明分期作为预后变量的价值，可用于评估生存、社会经济地位、种族和民族差异。我们的目的是分析 PBCR 提取口腔和口咽肿瘤 TNM 的可行性。选择这些解剖部位是因为通过目视检查和触诊可以获得肿瘤的分期。大约 23%的参与 CI5-IX 的 PBCR 表示他们会收集所有癌症部位的 TNM 分期。我们分析了来自 13 个 PBCR 的 23935 例口腔（OCC）和口咽癌（OPC）病例。男性 OCC 的完整 TNM 分期为 52.7%，女性为 47.6%；对于 OPC，两性的分期均为 56%。OCC 和 OPC 的分期不完整比例在 22%至 25%之间。缺失率约为 18-27%（口腔最常见）。OCC 年龄≥70 岁的男性缺失分期的比例明显更高，OR 值为 1.64（1.39-1.94）。我们的结果表明，与 OCC 相比，OPC 更倾向于分期。即使可以通过目视检查进行诊断，但这些结果突出表明，分期信息可以作为获得医疗保健和诊断意识的可靠指标。我们的结果表明，PBCR 收集分期是可行的，尽管进一步的技术培训和国际推荐采用 TNM 分期作为 PBCR 的标准变量，以提高该信息的完整性。
