Department of Conservative Dentistry, University Hospital Heidelberg, Heidelberg, Germany.
PLoS One. 2013;8(1):e53415. doi: 10.1371/journal.pone.0053415. Epub 2013 Jan 18.
The purpose of the present study was to describe the survival of patients diagnosed with oral cavity cancer in Germany. The analyses relied on data from eleven population-based cancer registries in Germany covering a population of 33 million inhabitants. Patients with a diagnosis of oral cavity cancer (ICD-10: C00-06) between 1997 and 2006 are included. Period analysis for 2002-2006 was applied to estimate five-year age-standardized relative survival, taking into account patients' sex as well as grade and tumor stage. Overall five-year relative survival for oral cavity cancer patients was 54.6%. According to tumor localization, five-year survival was 86.5% for lip cancer, 48.1% for tongue cancer and 51.7% for other regions of the oral cavity. Differences in survival were identified with respect to age, sex, tumor grade and stage. The present study is the first to provide a comprehensive overview on survival of oral cavity cancer patients in Germany.
本研究旨在描述德国口腔癌患者的生存情况。分析所依据的数据来自德国 11 个基于人群的癌症登记处,覆盖了 3300 万居民。纳入了 1997 年至 2006 年间诊断为口腔癌(ICD-10:C00-06)的患者。采用 2002-2006 年的期间分析来估计 5 年年龄标准化相对生存率,考虑到患者的性别以及肿瘤分级和分期。口腔癌患者的总体 5 年相对生存率为 54.6%。根据肿瘤定位,唇癌的 5 年生存率为 86.5%,舌癌为 48.1%,口腔其他部位为 51.7%。生存率存在年龄、性别、肿瘤分级和分期的差异。本研究首次全面概述了德国口腔癌患者的生存情况。