Department of Ophthalmology, Aberdeen Royal Infirmary, Aberdeen, UK.
Ophthalmologica. 2010;224(6):347-53. doi: 10.1159/000313816. Epub 2010 May 4.
BACKGROUND/AIMS: To assess the outcomes and complications of endotamponade with Oxane HD following retinal detachment repair.
Retrospective consecutive case series of inferior retinal detachment with Oxane HD endotamponade within a 3-year period.
Case notes for 18 eyes of 18 patients were reviewed. Four (22.2%) were total retinal detachments and 13 (72.2%) had proliferative vitreoretinopathy. The mean Oxane HD endotamponade and follow-up durations were 27 ± 38 and 66 ± 39 weeks, respectively. The eventual anatomic success rate was 77.8%, but without any significant difference in vision. Postoperative complications occurred in 14 (77.8%), including emulsification (6 eyes; 33.3%), epiretinal membrane (5 eyes; 27.8%), and posterior capsular opacification (4 eyes; 22.2%). Of the 14 eyes requiring intraoperative perfluorodecalin, 12 (85.7%) developed complications; all 5 (100%) eyes with direct exchange of perfluorodecalin with Oxane HD developed complications.
Although useful for inferior retinal detachments, Oxane HD was associated with a relatively high rate of emulsification when compared to other series. Our series also suggests that prior use of perfluorodecalin intraoperatively, and in particular direct exchange of perfluorodecalin with Oxane HD, may be associated with an increased risk of intraocular complications.
背景/目的：评估视网膜脱离修复后使用 Oxane HD 进行眼内填塞的结果和并发症。
回顾性连续病例系列研究，纳入了 3 年内使用 Oxane HD 进行眼内填塞的下视网膜脱离病例。
对 18 例 18 只眼的病例记录进行了回顾。其中 4 只眼（22.2%）为全视网膜脱离，13 只眼（72.2%）有增生性玻璃体视网膜病变。平均 Oxane HD 眼内填塞和随访时间分别为 27 ± 38 周和 66 ± 39 周。最终解剖成功率为 77.8%，但视力无显著差异。14 只眼（77.8%）发生了术后并发症，包括乳化（6 只眼；33.3%）、视网膜内膜（5 只眼；27.8%）和后囊膜混浊（4 只眼；22.2%）。在需要术中使用全氟萘烷的 14 只眼中，有 12 只眼（85.7%）发生了并发症；所有 5 只眼（100%）直接用全氟萘烷交换 Oxane HD 的眼均发生了并发症。
尽管 Oxane HD 对下视网膜脱离有用，但与其他系列相比，其乳化发生率相对较高。本系列还表明，术中先前使用全氟萘烷，特别是直接用全氟萘烷交换 Oxane HD，可能会增加眼内并发症的风险。
