Panieri E, Rode H, Millar A J, Cywes S
Department of Paediatric Surgery, University of Cape Town, Institute of Child Health, Red Cross War Memorial Children's Hospital, 7700 Rondebosch, Cape Town, South Africa.
Pediatr Surg Int. 1998 Jul;13(5-6):336-40. doi: 10.1007/s003830050333.
The accidental ingestion of corrosive agents is a major cause of oesophageal strictures in children. The mainstay of treatment is repeated dilatations. Despite this, a significant number of patients eventually require oesophageal bypass. We reviewed the records of all cases managed with this condition at the University of Cape Town teaching hospitals between 1976 and 1994. Dilatation therapy alone was successful in 14 out of 39 patients (41%). Morbidity of failed dilatation therapy included repeated hospital admissions over an average 11.5 months and 17 dilatations each. Oesophageal perforations occurred in 7 cases (18%). Early factors predictive of failure of conservative treatment were: delay in presentation of more than 1 month; severe pharyngo-oesophageal burns requiring a tracheostomy; oesophageal perforation; and a stricture longer than 5 cm on radiological assessment. The size of dilators accepted during early bougienage also correlated with eventual outcome. These criteria may be useful in predicting which patients will not respond to repeated dilatations. Early surgical intervention in such cases will prevent fruitless dilatations and related complications.
腐蚀性物质的意外摄入是儿童食管狭窄的主要原因。治疗的主要方法是反复扩张。尽管如此,仍有相当数量的患者最终需要进行食管旁路手术。我们回顾了1976年至1994年间在开普敦大学教学医院接受这种疾病治疗的所有病例记录。仅扩张治疗在39例患者中有14例成功(41%)。扩张治疗失败的并发症包括平均11.5个月内多次住院,每次平均进行17次扩张。7例(18%)发生食管穿孔。保守治疗失败的早期预测因素为:就诊延迟超过1个月;严重的咽喉食管烧伤需要气管切开术;食管穿孔;以及放射学评估显示狭窄长度超过5 cm。早期探条扩张时所接受的扩张器大小也与最终结果相关。这些标准可能有助于预测哪些患者对反复扩张无反应。在此类病例中早期进行手术干预将避免无效的扩张及相关并发症。