v Neindorff M
Klinik und Poliklinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307 Dresden, Deutschland.
Anaesthesist. 2010 May;59(5):479-90. doi: 10.1007/s00101-010-1732-8.
The choice of anesthesia procedure for surgical interventions in pregnancy is particularly important considering the responsibility for the unborn child and the patient. Uncertainties with the treatment of this patient group and lacking routine are common. Nevertheless, 0.5-2% of pregnant women require non-gynecological surgery. In this respect knowledge about the interrelationship between physiological changes and pharmacological effects with potentially negative impact for the embryo, fetus or neonate is of particular importance. In this article the physiology relevant for anesthesia during pregnancy is discussed and commonly used drugs are reviewed to enable anesthesiologists to formulate concepts to preclude adverse effects for the mother and child and to provide an adequate therapy.
考虑到对未出生胎儿和患者的责任，妊娠期间手术干预的麻醉方法选择尤为重要。对这一患者群体进行治疗时存在不确定性且缺乏常规做法是常见现象。尽管如此，仍有0.5% - 2%的孕妇需要进行非妇科手术。在这方面，了解生理变化与药理作用之间的相互关系，以及这些关系对胚胎、胎儿或新生儿可能产生的负面影响尤为重要。本文将讨论妊娠期间与麻醉相关的生理学，并对常用药物进行综述，以使麻醉医生能够制定概念，预防对母婴的不良影响，并提供充分的治疗。
