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光动力疗法用于前列腺的局灶性消融。

Photodynamic therapy for focal ablation of the prostate.

机构信息

Division of Surgery and Interventional Sciences, National Medical Laser Centre, University College London, Charles Bell House, 67-73 Riding House Street, London W1W 7EJ, UK.

出版信息

World J Urol. 2010 Oct;28(5):571-6. doi: 10.1007/s00345-010-0554-2. Epub 2010 May 9.

DOI:10.1007/s00345-010-0554-2
PMID:20454966
Abstract

Although in early stages of clinical development, photodynamic therapy (PDT) shows promise in delivering focal treatment of both primary and post-radiotherapy prostate cancer. This article will review the mechanism of action of PDT, previous research using PDT for treating prostate cancer including the development of newer vascular-acting photosensitizers, and the potential advantages and disadvantages of PDT in delivering focal therapy.

摘要

虽然光动力疗法（PDT）仍处于临床开发的早期阶段，但它在提供原发性和放疗后前列腺癌的局部治疗方面显示出了前景。本文将回顾 PDT 的作用机制、以前使用 PDT 治疗前列腺癌的研究，包括新型血管作用光敏剂的发展，以及 PDT 在提供局部治疗方面的潜在优缺点。

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Contrast-enhanced ultrasonography for real-time monitoring of interstitial laser thermal therapy in the focal treatment of prostate cancer.超声造影用于前列腺癌局部治疗中激光间质热疗的实时监测
Can Urol Assoc J. 2009 Apr;3(2):125-30. doi: 10.5489/cuaj.1044.
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Towards accurate in vivo spectroscopy of the human prostate.迈向人体前列腺精确的体内光谱分析。
J Biophotonics. 2008 Aug;1(3):200-3. doi: 10.1002/jbio.200710025.
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Motexafin lutetium-photodynamic therapy of prostate cancer: short- and long-term effects on prostate-specific antigen.
Cancers (Basel). 2021 Sep 3;13(17):4447. doi: 10.3390/cancers13174447.
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MRI guided procedure planning and 3D simulation for partial gland cryoablation of the prostate: a pilot study.磁共振成像引导下前列腺部分腺体冷冻消融的手术规划与三维模拟：一项初步研究
3D Print Med. 2020 Nov 3;6(1):33. doi: 10.1186/s41205-020-00085-2.
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Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?基于金属的光动力治疗光敏剂：多模态肿瘤学的未来？
Curr Opin Chem Biol. 2020 Jun;56:23-27. doi: 10.1016/j.cbpa.2019.10.004. Epub 2019 Nov 20.
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Robotic System for MRI-guided Focal Laser Ablation in the Prostate.用于前列腺磁共振成像引导下聚焦激光消融的机器人系统。
IEEE ASME Trans Mechatron. 2017 Feb;22(1):107-114. doi: 10.1109/TMECH.2016.2611570. Epub 2016 Sep 22.
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Photosensitizers in prostate cancer therapy.前列腺癌治疗中的光敏剂。
Oncotarget. 2017 May 2;8(18):30524-30538. doi: 10.18632/oncotarget.15496.
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J Urol. 2016 Oct;196(4):1096-104. doi: 10.1016/j.juro.2016.05.113. Epub 2016 Jun 9.
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World J Methodol. 2016 Mar 26;6(1):65-76. doi: 10.5662/wjm.v6.i1.65.
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