Algorri José Francisco, Ochoa Mario, Roldán-Varona Pablo, Rodríguez-Cobo Luís, López-Higuera José Miguel
Photonics Engineering Group, University of Cantabria, 39005 Santander, Spain.
CIBER-bbn, Institute of Health Carlos III, 28029 Madrid, Spain.
Cancers (Basel). 2021 Sep 3;13(17):4447. doi: 10.3390/cancers13174447.
Photodynamic therapy (PDT) is a promising therapy against cancer. Even though it has been investigated for more than 100 years, scientific publications have grown exponentially in the last two decades. For this reason, we present a brief compendium of reviews of the last two decades classified under different topics, namely, overviews, reviews about specific cancers, and meta-analyses of photosensitisers, PDT mechanisms, dosimetry, and light sources. The key issues and main conclusions are summarized, including ways and means to improve therapy and outcomes. Due to the broad scope of this work and it being the first time that a compendium of the latest reviews has been performed for PDT, it may be of interest to a wide audience.
光动力疗法（PDT）是一种很有前景的癌症治疗方法。尽管它已经被研究了100多年，但在过去二十年里，科学出版物呈指数级增长。因此，我们简要汇编了过去二十年按不同主题分类的综述，即概述、关于特定癌症的综述以及对光敏剂、PDT机制、剂量学和光源的荟萃分析。总结了关键问题和主要结论，包括改善治疗和结果的方法和手段。由于这项工作的范围广泛，且这是首次对PDT的最新综述进行汇编，它可能会引起广大读者的兴趣。
