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白内障导致的视力损害与健康相关生活质量:菲律宾一项病例对照研究的结果

Visual impairment from cataract and health related quality of life: results from a case-control study in the Philippines.

作者信息

Polack Sarah, Eusebio Cristina, Fletcher Astrid, Foster Allen, Kuper Hannah

机构信息

London School of Hygiene & Tropical Medicine, London, UK.

出版信息

Ophthalmic Epidemiol. 2010 Jun;17(3):152-9. doi: 10.3109/09286581003731536.

Abstract

PURPOSE

To evaluate a vision related quality of life (VRQoL) scale, the World Health Organization Prevention of Blindness and Deafness Visual Function-20 (WHO/ PBD VF20) and describe the relationship between visual impairment from cataract and vision related and generic Health Related Quality of Life (HRQoL) in a case-control study of adults aged > or = 50 years in the Philippines.

METHODS

Two hundred and thirty eight population based persons visually impaired from cataract and 163 age- gender- matched controls with normal vision were interviewed using the WHO/PBD VF20 and European Quality of Life (EuroQol) questionnaire (an HRQoL). The WHO/PBD VF20 was evaluated using standard psychometric tests.

RESULTS

The WHO/PBD VF20 had good item acceptability and validity. Cases had significantly poorer VRQoL than controls and worsening Visual Acuity (VA) was associated with worsening VRQoL. The general functioning subscale had good internal consistency. The psychosocial sub-scale had a Cronbach's alpha of 0.61, just below the generally accepted criteria of 0.70. Cases were much more likely than controls to report problems with the Euroqol five descriptive domains (EQ-5D)and had significantly poorer self-rated health.

CONCLUSIONS

The study supports the use of the WHO/PBD VF20 in a Philippine population and highlights the worsening VRQoL associated with cataract vision loss. The poorer generic HRQoL among cases compared to controls indicates an impact of visual impairment on perceived health and well-being, beyond vision-specific experience.

摘要

目的

评估一种与视力相关的生活质量(VRQoL)量表,即世界卫生组织防盲防聋视觉功能-20量表(WHO/PBD VF20),并在一项针对菲律宾50岁及以上成年人的病例对照研究中,描述白内障所致视力损害与视力相关及一般健康相关生活质量(HRQoL)之间的关系。

方法

使用WHO/PBD VF20和欧洲生活质量问卷(EuroQol,一种HRQoL问卷),对238名基于人群的白内障致视力受损者以及163名年龄和性别匹配的视力正常对照者进行访谈。使用标准心理测量测试对WHO/PBD VF20进行评估。

结果

WHO/PBD VF20具有良好的项目可接受性和有效性。病例组的VRQoL显著低于对照组,视力(VA)恶化与VRQoL恶化相关。一般功能子量表具有良好的内部一致性。心理社会子量表的Cronbach's alpha系数为0.61,略低于普遍接受的0.70标准。与对照组相比,病例组更有可能报告在Euroqol五个描述性领域(EQ-5D)存在问题,且自我评定的健康状况明显较差。

结论

该研究支持在菲律宾人群中使用WHO/PBD VF20,并强调了与白内障视力丧失相关的VRQoL恶化。与对照组相比,病例组较差的一般HRQoL表明视力损害对感知健康和幸福感有影响,这种影响超出了特定视力方面的体验。

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