阿根廷人群 10 个 X-STR 基因座遗传分析。
Genetic analysis of 10 X-STRs in Argentinian population.
机构信息
Cátedra de Genética y Biología Molecular, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.
出版信息
Forensic Sci Int Genet. 2011 Jan;5(1):e14-6. doi: 10.1016/j.fsigen.2009.11.005. Epub 2010 Jan 4.
A set of 200 samples, 100 males and 100 females, obtained from unrelated Argentinean donors were analyzed using 10 X-STRs-DXS8378, DXS9898, DXS7133, GATA31E08, GATA172D05, DXS7423, DXS6809, DXS7132, DXS9902 and DXS6789-in order to obtain allele frequencies. Statistical analysis was performed using Powerstats and Arlequin software. The population showed no deviation from Hardy Weinberg equilibrium at all loci analyzed. Allele frequencies were compared with Spanish and Portuguese sample sets showing no statistical significant differences in four of the 10 markers analyzed. The most polymorphic marker was DXS6809 and the high values of combined power of exclusion (99.9993355% in trios and 99.9715450% in duos) reinforce the usefulness of this set of markers for kinship test and human identification.
从无关的阿根廷供体中获得了一组 200 个样本，其中包括 100 名男性和 100 名女性，使用 10 个 X-STR 标志物（DXS8378、DXS9898、DXS7133、GATA31E08、GATA172D05、DXS7423、DXS6809、DXS7132、DXS9902 和 DXS6789）对其进行分析，以获得等位基因频率。使用 Powerstats 和 Arlequin 软件进行统计分析。在所有分析的基因座上，人群均未偏离哈迪-温伯格平衡。与西班牙和葡萄牙的样本集进行比较，在分析的 10 个标记物中的 4 个中没有统计学显著差异。最多态性的标记物是 DXS6809，排除的综合能力（三亲的 99.9993355%和二亲的 99.9715450%）值很高，这增强了这组标记物在亲缘关系测试和人类识别方面的有用性。
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