Suppr超能文献

西班牙人群样本中10个X染色体短串联重复序列的遗传数据。

Genetic data of 10 X-STRs in a Spanish population sample.

作者信息

Aler M, Sánchez-Diz P, Gomes I, Gisbert M, Carracedo A, Amorim A, Gusmão L

机构信息

Forensic Genetics U.D. Legal Medicine, University of Valencia E.G., Valencia, Spain.

出版信息

Forensic Sci Int. 2007 Dec 20;173(2-3):193-6. doi: 10.1016/j.forsciint.2006.10.023. Epub 2007 Feb 22.

Abstract

In this work, we present population genetic data of 10 X-chromosome STRs (DXS8378, DXS9898, DXS8377, HPRTB, GATA172D05, DXS7423, DXS6809, DXS7132, DXS101 and DXS6789) obtained from sample of 145 unrelated female individuals belonging to Valencia (Spain), a region located in the east of the Iberian Peninsula. All the markers studied present high genetic diversities, similar to those previously reported in other European population samples. No deviations from Hardy-Weinberg equilibrium were observed, with the exception of DXS101 locus. Allele frequencies and parameters of forensic interest for each X-STR were calculated. High mean exclusion chance and power of discrimination values were obtained by combining these 10 X-linked markers. Population comparisons (exact test of population differentiation; pairwise genetic distances) were carried out and low genetic distances were found between our sample and those from other Spanish or European regions.

摘要

在这项研究中,我们展示了从145名来自西班牙巴伦西亚(位于伊比利亚半岛东部的一个地区)的无关女性个体样本中获得的10个X染色体短串联重复序列(DXS8378、DXS9898、DXS8377、HPRTB、GATA172D05、DXS7423、DXS6809、DXS7132、DXS101和DXS6789)的群体遗传数据。所有研究的标记均呈现出高遗传多样性,与先前在其他欧洲群体样本中报道的相似。除DXS101基因座外,未观察到偏离哈迪-温伯格平衡的情况。计算了每个X-STR的等位基因频率和法医相关参数。通过组合这10个X连锁标记获得了较高的平均排除机会和鉴别力值。进行了群体比较(群体分化的精确检验;成对遗传距离),发现我们的样本与来自其他西班牙或欧洲地区的样本之间的遗传距离较低。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验