Gu Shanzhi, Li Shengbin
Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an Shaanxi 710061, China.
Forensic Sci Int. 2006 Apr 20;158(1):72-5. doi: 10.1016/j.forsciint.2005.04.026. Epub 2005 Nov 8.
X-chromosome STR, known as microsatellite, is a kind of the most information genetic markers for specific biological materials. Because the size of X-chromosome STR alleles is small, generally including 100-350 nucleotides, it is relatively easy to be amplified and detected with high sensitivity. We have investigated 10 X-chromosome STR loci in an Ewenke ethnic population who live in Neimengu of northeast China. Allele frequencies of 10 X-chromosome STR loci, including DXS7133, DXS6799, DXS8378, DXS7423, DXS6804, HPRTB, DXS7424, DXS7132, DXS6789 and DXS101, were obtained from healthy unrelated individuals (45 females and 53 males) of Ewenke ethnic group.
X染色体短串联重复序列(STR),即微卫星,是针对特定生物材料的一种信息含量最为丰富的遗传标记。由于X染色体STR等位基因的大小较小,通常包含100 - 350个核苷酸,因此相对容易进行扩增且检测灵敏度高。我们对居住在中国东北内蒙古地区的鄂温克族人群中的10个X染色体STR基因座进行了研究。从鄂温克族健康无关个体(45名女性和53名男性)中获得了10个X染色体STR基因座的等位基因频率,这些基因座包括DXS7133、DXS6799、DXS8378、DXS7423、DXS6804、HPRTB、DXS7424、DXS7132、DXS6789和DXS101。