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特立帕肽治疗隐性营养不良型大疱性表皮松解症患者的严重骨质疏松症。

Severe osteoporosis treated with teriparatide in a patient affected by recessive epidermolysis bullosa dystrophica.

机构信息

Orthopedic and Traumatology Unit, Department of Clinical Methodology and Surgical Techniques, University of Bari, Bari, Italy.

出版信息

Osteoporos Int. 2011 Mar;22(3):1003-6. doi: 10.1007/s00198-010-1278-2. Epub 2010 May 11.

Abstract

In this work, we describe the clinical and instrumental results of our experience, the first reported in the literature, of the administration of teriparatide to treat severe osteoporosis secondary to epidermolysis bullosa. Already after 2 months of therapy, the patient, a 20-year-old affected by a recessive form of epidermolysis bullosa dystrophica, had less pain and a functional recovery resulting in an improved autonomy; a satisfactory increase in the densitometric values was documented.

摘要

在这项工作中,我们描述了我们的经验的临床和仪器结果,这是文献中首次报道的用特立帕肽治疗大疱性表皮松解症继发的严重骨质疏松症。在治疗 2 个月后,患者,一名 20 岁的隐性营养不良性大疱性表皮松解症患者,疼痛减轻,功能恢复,从而提高了生活的自主性;骨密度值的显著增加得到了证实。

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