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2
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3
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本文引用的文献

1
Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition of Carbonyl Compounds and Imines.通过催化氢化和转移氢化形成碳-碳键：羰基化合物和亚胺的乙烯基化、烯丙基化及烯醇盐加成反应
Aldrichimica Acta. 2008;41(4):95-104.
2
Formation of C-C Bonds via Ruthenium Catalyzed Transfer Hydrogenation: Carbonyl Addition from the Alcohol or Aldehyde Oxidation Level.通过钌催化转移氢化形成碳-碳键：来自醇或醛氧化水平的羰基加成
Chem Lett. 2008;37(11):1102-1107. doi: 10.1246/cl.2008.1102.
3
Hydroacylation of 2-Butyne from the Alcohol or Aldehyde Oxidation Level via Ruthenium Catalyzed C-C Bond Forming Transfer Hydrogenation.通过钌催化的碳-碳键形成转移氢化反应，从醇或醛氧化水平对2-丁炔进行氢酰化反应。
Tetrahedron. 2009 Jun 27;65(26):5024-5029. doi: 10.1016/j.tet.2009.03.068.
4
Synthesis of 2-hydroxymethyl ketones by ruthenium hydride-catalyzed cross-coupling reaction of alpha,beta-unsaturated aldehydes with primary alcohols.铑氢化物催化的α,β-不饱和醛与伯醇的交叉偶联反应合成 2-羟甲基酮。
Org Lett. 2010 Jan 1;12(1):1-3. doi: 10.1021/ol902289r.
5
Dehydrogenation as a substrate-activating strategy in homogeneous transition-metal catalysis.脱氢反应作为均相过渡金属催化中一种底物活化策略。
Chem Rev. 2010 Feb 10;110(2):681-703. doi: 10.1021/cr900202j.
6
Hydrogen autotransfer in the N-alkylation of amines and related compounds using alcohols and amines as electrophiles.使用醇类和胺类作为亲电试剂时，胺类及相关化合物N-烷基化反应中的氢自动转移。
Chem Rev. 2010 Mar 10;110(3):1611-41. doi: 10.1021/cr9002159.
7
Unexpected formation of a cyclopentadienylruthenium alkoxycarbonyl complex with a coordinated C=C bond.意外形成具有配位碳碳双键的环戊二烯基钌烷氧羰基配合物。
J Am Chem Soc. 2009 Sep 30;131(38):13622-4. doi: 10.1021/ja905741w.
8
Protecting-group-free synthesis of 3-tert-prenylated oxindoles: contiguous all-carbon quaternary centers via tertiary neopentyl substitution.3-叔戊烯基异吲哚酮的无保护基合成：通过叔新戊基取代形成连续的全碳季碳中心
Org Lett. 2009 Oct 15;11(20):4485-7. doi: 10.1021/ol9018562.
9
All-carbon quaternary centers via ruthenium-catalyzed hydroxymethylation of 2-substituted butadienes mediated by formaldehyde: beyond hydroformylation.通过甲醛介导的钌催化2-取代丁二烯的羟甲基化反应构建全碳季碳中心：超越氢甲酰化反应
J Am Chem Soc. 2009 Aug 5;131(30):10366-7. doi: 10.1021/ja904124b.
10
Concise synthesis of the bryostatin A-ring via consecutive C-C bond forming transfer hydrogenations.通过连续的碳-碳键形成转移氢化反应简洁合成苔藓抑素A环。
Org Lett. 2009 Jul 16;11(14):3108-11. doi: 10.1021/ol901096d.

烯丙酰胺羟烷化反应：通过钌催化的羰基反氨烯丙基化反应合成 1,2-氨基醇。

Allenamide hydro-hydroxyalkylation: 1,2-amino alcohols via ruthenium-catalyzed carbonyl anti-aminoallylation.

机构信息

University of Texas at Austin, Department of Chemistry and Biochemistry, Austin, Texas 78712, USA.

出版信息

Org Lett. 2010 Jun 4;12(11):2514-6. doi: 10.1021/ol1007235.

DOI:10.1021/ol1007235
PMID:20459077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2881554/
Abstract

Exposure of alcohols to allenamides in the presence of RuHCl(CO)(PPh(3))(3) and dippf [dippf = bis(diisopropylphosphino)ferrocene] results in hydrogen transfer to generate aldehyde-allylruthenium pairs, which engage in C-C coupling to form products of carbonyl aminoallylation as single anti-diastereomers.

摘要

醇在 RuHCl(CO)(PPh(3))(3) 和 dippf（二异丙基膦二茂铁）存在下与烯丙酰胺接触会发生氢转移，生成醛-烯丙基钌对，它们进行 C-C 偶联形成羰基氨基烯丙化产物的单非对映异构体。