GE Global Research, 1 Research Circle, Niskayuna, New York 12309, USA.
J Biomed Opt. 2010 Mar-Apr;15(2):020509. doi: 10.1117/1.3378128.
Fluorescence image-guided surgery (FIGS) is an emerging technique in oncology, neurology, and cardiology. To adapt intraoperative imaging for various surgical applications, increasingly flexible and compact FIGS instruments are necessary. We present a compact, portable FIGS system and demonstrate its use in cardiovascular mapping in a preclinical model of myocardial ischemia. Our system uses fiber optic delivery of laser diode excitation, custom optics with high collection efficiency, and compact consumer-grade cameras as a low-cost and compact alternative to open surgical FIGS systems. Dramatic size and weight reduction increases flexibility and access, and allows for handheld use or unobtrusive positioning over the surgical field.
荧光图像引导手术(FIGS)是肿瘤学、神经学和心脏病学领域的一项新兴技术。为了使术中成像适应各种手术应用,需要越来越灵活和紧凑的 FIGS 仪器。我们展示了一种紧凑、便携式的 FIGS 系统,并在心肌缺血的临床前模型中演示了其在心血管映射中的应用。我们的系统使用光纤输送激光二极管激发,采用具有高效率收集的定制光学器件,以及紧凑型消费级相机,作为开放式手术 FIGS 系统的低成本和紧凑替代方案。显著的尺寸和重量减轻增加了灵活性和可及性,并允许手持使用或在手术区域上方进行隐蔽定位。